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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007804744> ?p ?o ?g. }

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• W2007804744 abstract "A series of tubulysin analogs in which one of the stereogenic centers of tubuphenylalanine was eliminated were synthesized. All compounds were tested for antiproliferative activity towards ovarian cancer cells and for inhibition of tubulin polymerization. The dimethyl analogs were generally more active than the desmethyl analogs, and four analogs have tubulin polymerization IC(50) values similar to combretastatin A4 and the hemiasterlin analog HTI-286." @default.
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• W2007804744 date "2008-05-01" @default.
• W2007804744 modified "2023-10-01" @default.
• W2007804744 title "Tubulysin analogs incorporating desmethyl and dimethyl tubuphenylalanine derivatives" @default.
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• W2007804744 doi "https://doi.org/10.1016/j.bmcl.2008.03.046" @default.
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