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- W2007842611 abstract "To evaluate the effect of metallic implant on the dose calculation for radiation therapy in the patients with metallic implants and to search for the way to reduce its effect. In our study, we made a phantom in which titanium implants were inserted in similar position to spinal posterior/posterolateral fusion. We compared the calculated dose of treatment planning systems and the measured dose in radiation therapy equipments. We used three kinds of CT (kilovoltage CT, extended-scaled kilovoltage CT and megavoltage CT) and three kinds of radiation therapy equipments (ARTISTE (Siemens, Berlin, Germany), Tomotherapy (TomoTherapy, Madison, WI) and Cyberknife (Accuray, Sunnyvale, CA). For measurement of dose, we used an ionization chamber and a Gafchromic EBT film. The absolute dose which was measured using an ionization chamber at the isocenter in the titanium phantom was average 1.9% lower than in the reference phantom (p = 0.002). There was not statistically significant difference according to the kinds of CT images, radiation therapy equipments and the size of target. As the distance from the surface of the titanium implants becomes closer, the measured dose tends to be decreased (p < 0.001). There was a statistically significant difference among the kinds of CT images. The effect of metallic implants is less in the megavoltage CT than in the kilovoltage CT or extended-scaled kilovoltage CT (p = 0.063). The range of errors due to the titanium implants is beyond clinically acceptable range. In order to reduce the error of dose calculation, we recommend that the megavoltage CT should be used for treatment planning. In addition, to prescribe the dose for the target and the dose constraint for the organ at risk, it is necessary to consider the distance between the titanium implants and the targets or the organ at risk." @default.
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- W2007842611 date "2010-11-01" @default.
- W2007842611 modified "2023-10-06" @default.
- W2007842611 title "The Effect of Metallic Implants for the Radiation Therapy in the Spinal Tumor Patients with Metallic Spinal Implants" @default.
- W2007842611 doi "https://doi.org/10.1016/j.ijrobp.2010.07.1781" @default.
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