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- W2007889425 abstract "Dans le spectre des désordres microangiopathiques de la grossesse, le syndrome catastrophique des antiphospholipides (SCAP) tient une place particulière de par sa sévérité mettant en jeu le pronostic fœtal et maternel. Son atteinte multisystémique, en cas de présentation hépatique prédominante, peut être confondue avec un syndrome HELLP qui survient habituellement plus tard au cours de la grossesse. Nous rapportons une observation de SCAP probable avec atteinte hépatique chez une femme enceinte à 13 semaines d’aménorrhée, porteuse d’un syndrome des antiphospholipides (SAPL), et présentant des stigmates biologiques de syndrome HELLP. L’imagerie de l’atteinte hépatique, non spécifique, bien documentée chez notre patiente a permis une prise en charge thérapeutique précoce. Le SCAP et le syndrome HELLP sont des pathologies microthrombotiques sévères pouvant être associées. La distinction nosologique ne modifie pas la prise en charge qui constitue une urgence materno-fœtale, mais leur association impose un traitement immédiat plus agressif. Among microangiopathic disorders of pregnancy, catastrophic antiphospholipid syndrome (CAPS) is a maternal and fetal life-threatening disorder. Hepatic involvement of this multi-systemic disorder can be confused with HELLP syndrome, occurring usually later in the course of pregnancy. We report a case of probable CAPS with hepatic disease in a pregnant woman at 13 week's gestation, with antiphospholipid syndrome and biological features of HELLP syndrome. Unspecific hepatic imaging, well-described in our case allowed undelayed therapy. CAPS and HELLP syndrome, both severe microangiopathic disorders, may be associated. Nosological distinction does not modify treatment strategy, which is a maternal and foetal emergency, but their overlapping requires aggressive and early management." @default.
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- W2007889425 date "2009-03-01" @default.
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- W2007889425 title "Infarctus hépatiques associés à un syndrome HELLP précoce et un probable syndrome catastrophique des antiphospholipides" @default.
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- W2007889425 doi "https://doi.org/10.1016/j.revmed.2008.09.013" @default.
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