Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007935706> ?p ?o ?g. }
- W2007935706 endingPage "440" @default.
- W2007935706 startingPage "428" @default.
- W2007935706 abstract "The uteroferrin(Uf)-associated basic proteins (UfAP) are a group of three (Mr = 42K, 48K, and 50K) antigenically related, basic glycoproteins secreted by the porcine uterus under the influence of progesterone (P4) which exist as heterodimers (Mr = 80,000) with the iron-binding acid phosphatase, Uf. Several UfAP cDNA clones from a day-60 pregnant pig uterine endometrial cDNA library have been cloned and sequenced. The UfAP mRNA is approximately 1400 bases long and has a single open reading frame of 1251 bases with two start codons at positions 64 and 79 from the 5'-end. UfAP mRNA content of the endometrium increases as pregnancy proceeds, reaching maximum levels around day 70 and then remaining relatively constant in late gestation (days 70 to 110). The pro-form of the UfAP minus signal sequence appears to be 392 amino acids in length and has four potential N-linked glycosylation sites Asn107, Asn197, Asn243, and Asn315. Comparison of the NH2-terminal sequences of the individual UfAP poly-peptides with the amino acid sequence deduced from the cDNA has indicated a series of at least four posttranslational proteolytic processing steps which generate the various molecular forms of the UfAP. The deduced amino acid sequence of UfAP shares considerable identity with several protease inhibitors and hormone-binding proteins that are members of the serpin superfamily of proteins. The UfAP amino acid sequence also exhibits about 55% sequence identity with the P4-induced uterine milk proteins (UTMP) of the sheep. Since the UfAP and UTMP share many biosynthetic and structural features that include site of biosynthesis in the endometrium, P4-responsiveness, the presence of the mannose 6-phosphate lysosomal recognition marker, and considerable sequence similarity, the UfAP and the UTMP may have homologous function which for both still remains obscure." @default.
- W2007935706 created "2016-06-24" @default.
- W2007935706 creator A5030373564 @default.
- W2007935706 creator A5037315792 @default.
- W2007935706 creator A5051610716 @default.
- W2007935706 creator A5086904682 @default.
- W2007935706 date "1990-03-01" @default.
- W2007935706 modified "2023-10-17" @default.
- W2007935706 title "Molecular Cloning of the Uteroferrin-Associated Protein, a Major Progesterone-Induced Serpin Secreted by the Porcine Uterus, and the Expression of its mRNA during Pregnancy" @default.
- W2007935706 cites W135785445 @default.
- W2007935706 cites W1481643052 @default.
- W2007935706 cites W1489749316 @default.
- W2007935706 cites W1490300323 @default.
- W2007935706 cites W1501423905 @default.
- W2007935706 cites W1509743989 @default.
- W2007935706 cites W1517450192 @default.
- W2007935706 cites W1519921402 @default.
- W2007935706 cites W1523421186 @default.
- W2007935706 cites W1554807780 @default.
- W2007935706 cites W1589594958 @default.
- W2007935706 cites W1590478241 @default.
- W2007935706 cites W1605117581 @default.
- W2007935706 cites W1894312995 @default.
- W2007935706 cites W1932052686 @default.
- W2007935706 cites W1967479697 @default.
- W2007935706 cites W1973993781 @default.
- W2007935706 cites W1975304761 @default.
- W2007935706 cites W198565315 @default.
- W2007935706 cites W1987498081 @default.
- W2007935706 cites W2000439492 @default.
- W2007935706 cites W2001570522 @default.
- W2007935706 cites W2002527726 @default.
- W2007935706 cites W2002940954 @default.
- W2007935706 cites W2005393972 @default.
- W2007935706 cites W2012847227 @default.
- W2007935706 cites W2016902830 @default.
- W2007935706 cites W2025560515 @default.
- W2007935706 cites W2038352589 @default.
- W2007935706 cites W2042458290 @default.
- W2007935706 cites W2053418558 @default.
- W2007935706 cites W2054722981 @default.
- W2007935706 cites W2060333964 @default.
- W2007935706 cites W2065707216 @default.
- W2007935706 cites W2067596934 @default.
- W2007935706 cites W2072117969 @default.
- W2007935706 cites W2076239915 @default.
- W2007935706 cites W2091437216 @default.
- W2007935706 cites W2095450147 @default.
- W2007935706 cites W2100837269 @default.
- W2007935706 cites W2101108802 @default.
- W2007935706 cites W2117862502 @default.
- W2007935706 cites W2138270253 @default.
- W2007935706 cites W2138879032 @default.
- W2007935706 cites W2144634347 @default.
- W2007935706 cites W2148270916 @default.
- W2007935706 cites W2151590843 @default.
- W2007935706 cites W2157171673 @default.
- W2007935706 cites W2164464592 @default.
- W2007935706 cites W2170526750 @default.
- W2007935706 cites W2171011748 @default.
- W2007935706 cites W2504349734 @default.
- W2007935706 doi "https://doi.org/10.1210/mend-4-3-428" @default.
- W2007935706 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2342477" @default.
- W2007935706 hasPublicationYear "1990" @default.
- W2007935706 type Work @default.
- W2007935706 sameAs 2007935706 @default.
- W2007935706 citedByCount "38" @default.
- W2007935706 countsByYear W20079357062015 @default.
- W2007935706 countsByYear W20079357062017 @default.
- W2007935706 crossrefType "journal-article" @default.
- W2007935706 hasAuthorship W2007935706A5030373564 @default.
- W2007935706 hasAuthorship W2007935706A5037315792 @default.
- W2007935706 hasAuthorship W2007935706A5051610716 @default.
- W2007935706 hasAuthorship W2007935706A5086904682 @default.
- W2007935706 hasBestOaLocation W20079357061 @default.
- W2007935706 hasConcept C104317684 @default.
- W2007935706 hasConcept C105580179 @default.
- W2007935706 hasConcept C10858879 @default.
- W2007935706 hasConcept C108625454 @default.
- W2007935706 hasConcept C153911025 @default.
- W2007935706 hasConcept C167625842 @default.
- W2007935706 hasConcept C181199279 @default.
- W2007935706 hasConcept C187882448 @default.
- W2007935706 hasConcept C2776714187 @default.
- W2007935706 hasConcept C2778965386 @default.
- W2007935706 hasConcept C515207424 @default.
- W2007935706 hasConcept C55493867 @default.
- W2007935706 hasConcept C86803240 @default.
- W2007935706 hasConceptScore W2007935706C104317684 @default.
- W2007935706 hasConceptScore W2007935706C105580179 @default.
- W2007935706 hasConceptScore W2007935706C10858879 @default.
- W2007935706 hasConceptScore W2007935706C108625454 @default.
- W2007935706 hasConceptScore W2007935706C153911025 @default.
- W2007935706 hasConceptScore W2007935706C167625842 @default.
- W2007935706 hasConceptScore W2007935706C181199279 @default.
- W2007935706 hasConceptScore W2007935706C187882448 @default.
- W2007935706 hasConceptScore W2007935706C2776714187 @default.
- W2007935706 hasConceptScore W2007935706C2778965386 @default.