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- W2007941017 abstract "Verapamil at 200 microM, prevented the respiratory stimulation, K+ loss, transmitter release, and 45Ca2+ entry into incubated synaptosomes evoked by veratrine (25 to 75 microM) or by high K+ (56 mM). Verapamil (100 microM) also blocked gamma-aminobutyric acid homoexchange, whilst tetrodotoxin was ineffective. Much lower concentrations of verapamil (less than 1 microM) blocked the 45Ca2+ entry caused by veratrine, but not its action in releasing neurotransmitter or K+. It is concluded that verapamil, at 30 to 200 microM, blocks active Na+ channels, thereby preventing depolarization. At greater than 1 microM, verapamil blocks Ca+ channels selectively." @default.
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- W2007941017 date "1983-02-01" @default.
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- W2007941017 title "The Suppression of Stimulus-Evoked Release of Amino Acid Neurotransmitters from Synaptosomes by Verapamil" @default.
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- W2007941017 doi "https://doi.org/10.1111/j.1471-4159.1983.tb11313.x" @default.
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