FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2007958306> ?p ?o ?g. }

• W2007958306 endingPage "1074" @default.
• W2007958306 startingPage "1065" @default.
• W2007958306 abstract "We examined whether estradiol and norethindrone hormone therapy (HT) prevented decline in delayed verbal recall in older women with normal to mildly impaired memory functioning. This was a 2-year, randomized, double-blind, placebo-controlled trial of 142 women aged 61-87, randomly assigned to receive 1 mg 17-beta estradiol daily and 0.35 mg norethindrone 3 days/week or daily placebo for 2 years. The primary outcome was short-delay verbal recall of the California Verbal Learning Test (CVLT). To look for differences in response to HT by baseline short-delay recall, we examined the primary outcome in participants grouped according to whether their baseline scores were below average for the age group or greater than or equal to this score and according to whether they met criteria for Mild Cognitive Impairment (MCI) or not. 133 women completed 1 year of the trial and 128 completed 2 years. Prespecified covariates in all repeated measures analyses of covariance (RANCOVA) included age, education, APOE epsilon4, and prior HT use. RANCOVA showed no overall significant treatment effects at year 1 or year 2. After testing for an interaction, which was significant (p=0.02), we found that women in the HT group who scored at or above the average showed significantly less decline than the placebo group in short-delay verbal recall after 1 year, p=0.007 and 2 years, p=0.01. No treatment effects were found in women below the average in either year. When grouped according to whether the participant met criteria for MCI, the interaction between treatment group and MCI subgroup was not significant. These results suggest that benefits of estrogen exposure may be limited to those with average to above average scores on the delayed verbal recall. HT dose and formulation may have contributed to these beneficial outcomes. Replication is warranted before recommendations can be made in the clinical setting." @default.
• W2007958306 created "2016-06-24" @default.
• W2007958306 creator A5014919500 @default.
• W2007958306 creator A5016139643 @default.
• W2007958306 creator A5040166156 @default.
• W2007958306 creator A5040671840 @default.
• W2007958306 creator A5059343766 @default.
• W2007958306 creator A5061852129 @default.
• W2007958306 creator A5068533952 @default.
• W2007958306 creator A5080238368 @default.
• W2007958306 creator A5081830188 @default.
• W2007958306 date "2009-08-01" @default.
• W2007958306 modified "2023-10-13" @default.
• W2007958306 title "A randomized double-blind trial of the effects of hormone therapy on delayed verbal recall in older women" @default.
• W2007958306 cites W129391377 @default.
• W2007958306 cites W1963783263 @default.
• W2007958306 cites W1965286338 @default.
• W2007958306 cites W1978061037 @default.
• W2007958306 cites W1981593391 @default.
• W2007958306 cites W1999647169 @default.
• W2007958306 cites W2002297740 @default.
• W2007958306 cites W2002580984 @default.
• W2007958306 cites W2004602458 @default.
• W2007958306 cites W2005016581 @default.
• W2007958306 cites W2018397167 @default.
• W2007958306 cites W2034639126 @default.
• W2007958306 cites W2041689445 @default.
• W2007958306 cites W2056745382 @default.
• W2007958306 cites W2067099461 @default.
• W2007958306 cites W2068998354 @default.
• W2007958306 cites W2084511339 @default.
• W2007958306 cites W2103780005 @default.
• W2007958306 cites W2110808599 @default.
• W2007958306 cites W2118825902 @default.
• W2007958306 cites W2120033816 @default.
• W2007958306 cites W2121683639 @default.
• W2007958306 cites W2123652060 @default.
• W2007958306 cites W2128339702 @default.
• W2007958306 cites W2131266318 @default.
• W2007958306 cites W2131722081 @default.
• W2007958306 cites W2134547791 @default.
• W2007958306 cites W2138720796 @default.
• W2007958306 cites W2139747033 @default.
• W2007958306 cites W2146126584 @default.
• W2007958306 cites W2156220037 @default.
• W2007958306 cites W2159122349 @default.
• W2007958306 cites W2160639597 @default.
• W2007958306 cites W2169308317 @default.
• W2007958306 cites W2169776352 @default.
• W2007958306 cites W4233067770 @default.
• W2007958306 doi "https://doi.org/10.1016/j.psyneuen.2009.02.009" @default.
• W2007958306 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19297102" @default.
• W2007958306 hasPublicationYear "2009" @default.
• W2007958306 type Work @default.
• W2007958306 sameAs 2007958306 @default.
• W2007958306 citedByCount "63" @default.
• W2007958306 countsByYear W20079583062012 @default.
• W2007958306 countsByYear W20079583062013 @default.
• W2007958306 countsByYear W20079583062014 @default.
• W2007958306 countsByYear W20079583062015 @default.
• W2007958306 countsByYear W20079583062016 @default.
• W2007958306 countsByYear W20079583062017 @default.
• W2007958306 countsByYear W20079583062018 @default.
• W2007958306 countsByYear W20079583062019 @default.
• W2007958306 countsByYear W20079583062020 @default.
• W2007958306 countsByYear W20079583062021 @default.
• W2007958306 countsByYear W20079583062022 @default.
• W2007958306 countsByYear W20079583062023 @default.
• W2007958306 crossrefType "journal-article" @default.
• W2007958306 hasAuthorship W2007958306A5014919500 @default.
• W2007958306 hasAuthorship W2007958306A5016139643 @default.
• W2007958306 hasAuthorship W2007958306A5040166156 @default.
• W2007958306 hasAuthorship W2007958306A5040671840 @default.
• W2007958306 hasAuthorship W2007958306A5059343766 @default.
• W2007958306 hasAuthorship W2007958306A5061852129 @default.
• W2007958306 hasAuthorship W2007958306A5068533952 @default.
• W2007958306 hasAuthorship W2007958306A5080238368 @default.
• W2007958306 hasAuthorship W2007958306A5081830188 @default.
• W2007958306 hasConcept C100660578 @default.
• W2007958306 hasConcept C105641010 @default.
• W2007958306 hasConcept C118552586 @default.
• W2007958306 hasConcept C126322002 @default.
• W2007958306 hasConcept C142724271 @default.
• W2007958306 hasConcept C15744967 @default.
• W2007958306 hasConcept C168563851 @default.
• W2007958306 hasConcept C169900460 @default.
• W2007958306 hasConcept C180747234 @default.
• W2007958306 hasConcept C204787440 @default.
• W2007958306 hasConcept C27081682 @default.
• W2007958306 hasConcept C2994444459 @default.
• W2007958306 hasConcept C71924100 @default.
• W2007958306 hasConcept C8290200 @default.
• W2007958306 hasConceptScore W2007958306C100660578 @default.
• W2007958306 hasConceptScore W2007958306C105641010 @default.
• W2007958306 hasConceptScore W2007958306C118552586 @default.
• W2007958306 hasConceptScore W2007958306C126322002 @default.
• W2007958306 hasConceptScore W2007958306C142724271 @default.
• W2007958306 hasConceptScore W2007958306C15744967 @default.

• next