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- W2007966234 abstract "Abstract The transport of choline and diethylcholine has been investigated in a cholinergic clone (S20F 3 ) of mouse neuroblastoma cells. Choline transport was linear for the first 20 min of incubation and was temperature dependent at low concentrations ( −5 M). Diethylcholine transport was linear for the first 10 min of incubation and was also temperature dependent at low concentrations. High affinity ( K m −6 M) and low affinity ( K m > 1 × 10 −5 M) components of transport were found for both compounds. The transport system had a greater apparent affinity (lower K m ) for choline than for diethylcholine (3-fold), but maximal transport velocities were about equal. Each compound competitively inhibited the other's high affinity transport. Hemicholinium (1 × 10 −5 M) slightly inhibited high affinity choline transport but triethylcholine (1 × 10 −6 −1 × 10 −4 M) did not. Choline transport was also found to be dependent on the pH and pCO 2 of the medium." @default.
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- W2007966234 title "Choline and diethylcholine transport into a cholinergic clone of neuroblastoma cells" @default.
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- W2007966234 doi "https://doi.org/10.1016/0006-2952(79)90106-0" @default.
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