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- W2007966650 abstract "Starting from experimental data on sequence, structure or biochemical properties of enzymes, protein design seeks to construct enzymes with desired activity, stability, specificity and selectivity. Two strategies are widely used to investigate sequence-structure-function relationships: statistical methods to analyse protein families or mutant libraries, and molecular modelling methods to study proteins and their interaction with ligands or substrates. On the basis of these methods, protein design has been successfully applied to fine-tune bottleneck enzymes in metabolic engineering and to design enzymes with new substrate spectra and new functions. However, constructing efficient metabolic pathways by integrating individual enzymes into a complex system is challenging. The field of synthetic biology is still in its infancy, but promising results have demonstrated the feasibility and usefulness of the concept." @default.
- W2007966650 created "2016-06-24" @default.
- W2007966650 creator A5067406221 @default.
- W2007966650 date "2011-10-01" @default.
- W2007966650 modified "2023-09-24" @default.
- W2007966650 title "Protein design in metabolic engineering and synthetic biology" @default.
- W2007966650 cites W1676564698 @default.
- W2007966650 cites W1860032350 @default.
- W2007966650 cites W1965113467 @default.
- W2007966650 cites W1967927324 @default.
- W2007966650 cites W1970441849 @default.
- W2007966650 cites W1972077573 @default.
- W2007966650 cites W1972205391 @default.
- W2007966650 cites W1973061137 @default.
- W2007966650 cites W1975348430 @default.
- W2007966650 cites W1976299542 @default.
- W2007966650 cites W1978119727 @default.
- W2007966650 cites W1980505389 @default.
- W2007966650 cites W1982197198 @default.
- W2007966650 cites W1984248485 @default.
- W2007966650 cites W1984467737 @default.
- W2007966650 cites W1986056153 @default.
- W2007966650 cites W1987696643 @default.
- W2007966650 cites W1989715615 @default.
- W2007966650 cites W1991835474 @default.
- W2007966650 cites W1992787746 @default.
- W2007966650 cites W1994593429 @default.
- W2007966650 cites W1996320633 @default.
- W2007966650 cites W1998532197 @default.
- W2007966650 cites W1999771835 @default.
- W2007966650 cites W2001602167 @default.
- W2007966650 cites W2004303971 @default.
- W2007966650 cites W2010004274 @default.
- W2007966650 cites W2010719165 @default.
- W2007966650 cites W2012968714 @default.
- W2007966650 cites W2015208014 @default.
- W2007966650 cites W2015492208 @default.
- W2007966650 cites W2023104761 @default.
- W2007966650 cites W2024872256 @default.
- W2007966650 cites W2033244353 @default.
- W2007966650 cites W2035757306 @default.
- W2007966650 cites W2044172420 @default.
- W2007966650 cites W2048875368 @default.
- W2007966650 cites W2049828254 @default.
- W2007966650 cites W2060194574 @default.
- W2007966650 cites W2068010831 @default.
- W2007966650 cites W2068143879 @default.
- W2007966650 cites W2068702674 @default.
- W2007966650 cites W2070167653 @default.
- W2007966650 cites W2070268621 @default.
- W2007966650 cites W2071861224 @default.
- W2007966650 cites W2074893062 @default.
- W2007966650 cites W2075944631 @default.
- W2007966650 cites W2076768880 @default.
- W2007966650 cites W2082260955 @default.
- W2007966650 cites W2086240831 @default.
- W2007966650 cites W2092414309 @default.
- W2007966650 cites W2093846844 @default.
- W2007966650 cites W2096375256 @default.
- W2007966650 cites W2096858057 @default.
- W2007966650 cites W2110198171 @default.
- W2007966650 cites W2114659756 @default.
- W2007966650 cites W2119292856 @default.
- W2007966650 cites W2125047266 @default.
- W2007966650 cites W2125581050 @default.
- W2007966650 cites W2128312954 @default.
- W2007966650 cites W2129450171 @default.
- W2007966650 cites W2133091545 @default.
- W2007966650 cites W2137612801 @default.
- W2007966650 cites W2138666829 @default.
- W2007966650 cites W2138992251 @default.
- W2007966650 cites W2139974139 @default.
- W2007966650 cites W2140012758 @default.
- W2007966650 cites W2147516046 @default.
- W2007966650 cites W2149291017 @default.
- W2007966650 cites W2152572188 @default.
- W2007966650 cites W2152964937 @default.
- W2007966650 cites W2153362524 @default.
- W2007966650 cites W2153650805 @default.
- W2007966650 cites W2156454061 @default.
- W2007966650 cites W2158033057 @default.
- W2007966650 cites W2159211381 @default.
- W2007966650 cites W2162039646 @default.
- W2007966650 cites W2169923025 @default.
- W2007966650 cites W2169989540 @default.
- W2007966650 cites W4212865600 @default.
- W2007966650 doi "https://doi.org/10.1016/j.copbio.2011.03.004" @default.
- W2007966650 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21514140" @default.
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