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• W2007968664 abstract "Novel 5-ring heterocyclic building blocks are synthesized. These can be incorporated into analogs of peptide antibiotics such as microcin B17, which is a potent DNA-gyrase inhibitor that exhibits eight thiazole and oxazole moieties. In particular, the syntheses of imidazole and bisoxazole amino acids as novel peptidomimetics are reported, this includes a new procedure for the oxidative conversion of the intermediates oxazoline, imidazoline as well as oxazole-oxazoline into the corresponding heteroaromatic compounds. A mixture of 1,8-diazabicyclo-[5.4.0.]-undec-7-ene carbon tetrachloride/acetonitrile and pyridine proved to be a very effective and mild agent." @default.
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• W2007968664 date "1999-09-01" @default.
• W2007968664 modified "2023-09-26" @default.
• W2007968664 title "Synthesis of thiazole, imidazole and oxazole containing amino acids for peptide backbone modification" @default.
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• W2007968664 doi "https://doi.org/10.1002/(sici)1099-1387(199909)5:9<392::aid-psc209>3.0.co;2-8" @default.
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