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- W2008003904 abstract "Reports from this laboratory have described studies over a period of 2 years with a nongoitrous, euthyroid, iodine-deficient population exhibiting elevated serum proteinbound iodine (PBI) values with normal serum butanol-extractable (BEI) values. The suggestion was made that the PBI elevation might be related to release of nonmetabolically active iodoprotein under increased TSH stimulation associated with iodine deficiency. If this were so, the increased PBI-BEI difference would be expected to decrease with iodine repletion and decrease of elevated thyroidal I131 uptake values. Accordingly, the effect of iodized salt was investigated in 20 of these subjects who had been exposed to iodine deficiency for an average period of 8 years. Ten received iodized salt only, 5 received an additional supplement of 180 mg desiccated thyroid daily, and 5 were given a daily supplement of iodine as KI alculated to equal the iodine in the thyroid medication. Urinary iodine excretion rose from a mean of 36 μg/day to 555 μg/..." @default.
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- W2008003904 date "1963-06-01" @default.
- W2008003904 modified "2023-09-27" @default.
- W2008003904 title "Iodine Repletion After Iodine Deficiency1" @default.
- W2008003904 doi "https://doi.org/10.1210/jcem-23-6-568" @default.
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