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- W2008006486 abstract "Lipase mediated asymmetric acetylation of σ-symmetrical 2-aryl-1,3-propanediols (1a–f), which were prepared conveniently via sequential Heck coupling between (5a–f) and (6), ozonolysis and reductive workup, provided the enantiomerically enriched monoacetates (2a–f) in good chemical and optical yields. These monoacetates (2a–f) were successfully converted into the biologically and pharmacologically interesting molecules, Baclofen (10), ar-turmerone (13), α-cuparenone (19), ent-aflatoxin B2 (24), ibuprofen (26), naproxen (28), and indolmycin (32) as optically active forms, respectively." @default.
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- W2008006486 date "1998-09-01" @default.
- W2008006486 modified "2023-10-03" @default.
- W2008006486 title "Lipase-mediated asymmetric acetylation of prochiral diols directed towards total syntheses of biologically active molecules" @default.
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- W2008006486 doi "https://doi.org/10.1016/s1381-1177(98)00031-9" @default.
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