Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008023265> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2008023265 endingPage "348" @default.
- W2008023265 startingPage "344" @default.
- W2008023265 abstract "Carbon-fiber microelectrodes and voltammetric methods have been used extensively for detection of neurochemical substances in brain tissue. We previously reported that calibration factors for dopamine obtained with these electrodes and fast-scan cyclic voltammetry are 2–3-fold higher in nonphysiological phosphate-buffered saline (PBS) than in artificial cerebrospinal fluid (ACSF) containing Ca2+and Mg2+. In the present report, we describe the media-dependence of calibration factors for other neurochemicals. Strikingly, whereas electrode sensitivities to dopamine and the indoleamine serotonin were lower in ACSF than in PBS, those for the acid metabolites of these neuro-transmitters were roughly 2-fold higher in ACSF than PBS. The data are consistent with adsorption or repulsion of these molecules by a negatively charged carbon-fiber electrode surface. One consequence of this pattern is that electrodes calibrated in PBS, rather than Ca2+- and Mg2+-containing media, will have a 2–6-fold lower amine-to-metabolite selectivity ratio in brain tissue than expected from in vitro calibration. More generally, the data suggest that the sensitivity of carbon-fiber-based microsensors to many organic molecules will be media-dependent. Thus, calibration in appropriate physiological media is essential for accurate tissue measurements." @default.
- W2008023265 created "2016-06-24" @default.
- W2008023265 creator A5011430847 @default.
- W2008023265 creator A5043025373 @default.
- W2008023265 date "1999-05-01" @default.
- W2008023265 modified "2023-10-03" @default.
- W2008023265 title "Calibration Factors for Cationic and Anionic Neurochemicals at Carbon-Fiber Microelectrodes are Oppositely Affected by the Presence of Ca2+and Mg2+" @default.
- W2008023265 cites W1591523569 @default.
- W2008023265 cites W1967657395 @default.
- W2008023265 cites W1968714816 @default.
- W2008023265 cites W1973131122 @default.
- W2008023265 cites W1984852777 @default.
- W2008023265 cites W1985803034 @default.
- W2008023265 cites W1986158789 @default.
- W2008023265 cites W1987530463 @default.
- W2008023265 cites W1989189523 @default.
- W2008023265 cites W1997568797 @default.
- W2008023265 cites W2011852728 @default.
- W2008023265 cites W2018699213 @default.
- W2008023265 cites W2022296180 @default.
- W2008023265 cites W2023873312 @default.
- W2008023265 cites W2033578337 @default.
- W2008023265 cites W2033994631 @default.
- W2008023265 cites W2035942303 @default.
- W2008023265 cites W2039957607 @default.
- W2008023265 cites W2045060416 @default.
- W2008023265 cites W2058856551 @default.
- W2008023265 cites W2066497793 @default.
- W2008023265 cites W2092919118 @default.
- W2008023265 cites W50884272 @default.
- W2008023265 cites W656278885 @default.
- W2008023265 doi "https://doi.org/10.1002/(sici)1521-4109(199905)11:5<344::aid-elan344>3.0.co;2-k" @default.
- W2008023265 hasPublicationYear "1999" @default.
- W2008023265 type Work @default.
- W2008023265 sameAs 2008023265 @default.
- W2008023265 citedByCount "15" @default.
- W2008023265 countsByYear W20080232652012 @default.
- W2008023265 countsByYear W20080232652013 @default.
- W2008023265 countsByYear W20080232652014 @default.
- W2008023265 countsByYear W20080232652017 @default.
- W2008023265 countsByYear W20080232652020 @default.
- W2008023265 crossrefType "journal-article" @default.
- W2008023265 hasAuthorship W2008023265A5011430847 @default.
- W2008023265 hasAuthorship W2008023265A5043025373 @default.
- W2008023265 hasConcept C111670793 @default.
- W2008023265 hasConcept C113196181 @default.
- W2008023265 hasConcept C12554922 @default.
- W2008023265 hasConcept C134018914 @default.
- W2008023265 hasConcept C147789679 @default.
- W2008023265 hasConcept C17525397 @default.
- W2008023265 hasConcept C185592680 @default.
- W2008023265 hasConcept C25876315 @default.
- W2008023265 hasConcept C2777477808 @default.
- W2008023265 hasConcept C2777869211 @default.
- W2008023265 hasConcept C2779603750 @default.
- W2008023265 hasConcept C43617362 @default.
- W2008023265 hasConcept C52859227 @default.
- W2008023265 hasConcept C55493867 @default.
- W2008023265 hasConcept C71924100 @default.
- W2008023265 hasConcept C86803240 @default.
- W2008023265 hasConceptScore W2008023265C111670793 @default.
- W2008023265 hasConceptScore W2008023265C113196181 @default.
- W2008023265 hasConceptScore W2008023265C12554922 @default.
- W2008023265 hasConceptScore W2008023265C134018914 @default.
- W2008023265 hasConceptScore W2008023265C147789679 @default.
- W2008023265 hasConceptScore W2008023265C17525397 @default.
- W2008023265 hasConceptScore W2008023265C185592680 @default.
- W2008023265 hasConceptScore W2008023265C25876315 @default.
- W2008023265 hasConceptScore W2008023265C2777477808 @default.
- W2008023265 hasConceptScore W2008023265C2777869211 @default.
- W2008023265 hasConceptScore W2008023265C2779603750 @default.
- W2008023265 hasConceptScore W2008023265C43617362 @default.
- W2008023265 hasConceptScore W2008023265C52859227 @default.
- W2008023265 hasConceptScore W2008023265C55493867 @default.
- W2008023265 hasConceptScore W2008023265C71924100 @default.
- W2008023265 hasConceptScore W2008023265C86803240 @default.
- W2008023265 hasIssue "5" @default.
- W2008023265 hasLocation W20080232651 @default.
- W2008023265 hasOpenAccess W2008023265 @default.
- W2008023265 hasPrimaryLocation W20080232651 @default.
- W2008023265 hasRelatedWork W1978001207 @default.
- W2008023265 hasRelatedWork W2005958769 @default.
- W2008023265 hasRelatedWork W2015665724 @default.
- W2008023265 hasRelatedWork W2082481978 @default.
- W2008023265 hasRelatedWork W2083954622 @default.
- W2008023265 hasRelatedWork W2368981901 @default.
- W2008023265 hasRelatedWork W2379699068 @default.
- W2008023265 hasRelatedWork W2497424241 @default.
- W2008023265 hasRelatedWork W2518307472 @default.
- W2008023265 hasRelatedWork W4230203098 @default.
- W2008023265 hasVolume "11" @default.
- W2008023265 isParatext "false" @default.
- W2008023265 isRetracted "false" @default.
- W2008023265 magId "2008023265" @default.
- W2008023265 workType "article" @default.