Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008025550> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2008025550 endingPage "198" @default.
- W2008025550 startingPage "195" @default.
- W2008025550 abstract "Exploring the (CAG)n expansion within IT 15 gene in Turkish Huntington's disease (HD) patients and its relation to downstream (CCG)n repeat polymorphism to elucidate population specific haplotypic heterogeneity.Twenty-seven patients with clinical diagnosis of HD from 19 families were sampled. The triplet repeats were evaluated by sizing the fluorescent PCR products on an ABI 310 capillary gel electrophoresis unit.The number of (CAG)n repeat expansions (range: 40-76, mean: 45.6+/-7) were inversely correlated with age of onset (r=-0.81, P<0.0001). The (CCG)n polymorphism in HD chromosomes was confined to (CCG)7 in all patients. In normal chromosomes CAG polymorphism was accumulated at a relatively higher range (mean: 19.3+/-2.9) together with the common occurrence of(CCG)7 and (CCG)10 alleles.The distribution range of the CAG and CCG repeat polymorphism in normal chromosomes and strong linkage disequilibrium between HD mutation and (CCG)7 haplotype provided a striking similarity to populations of western European descent." @default.
- W2008025550 created "2016-06-24" @default.
- W2008025550 creator A5021485368 @default.
- W2008025550 creator A5073217377 @default.
- W2008025550 creator A5086689881 @default.
- W2008025550 date "2009-01-29" @default.
- W2008025550 modified "2023-10-17" @default.
- W2008025550 title "The genetic analysis of Turkish patients with Huntington's disease" @default.
- W2008025550 cites W1943069293 @default.
- W2008025550 cites W1965271056 @default.
- W2008025550 cites W1966853606 @default.
- W2008025550 cites W1973055895 @default.
- W2008025550 cites W1999222814 @default.
- W2008025550 cites W2039376206 @default.
- W2008025550 cites W2094224318 @default.
- W2008025550 cites W2105248115 @default.
- W2008025550 cites W2106706966 @default.
- W2008025550 cites W2121642311 @default.
- W2008025550 cites W2121715853 @default.
- W2008025550 cites W2132479459 @default.
- W2008025550 cites W2153196213 @default.
- W2008025550 cites W2156243335 @default.
- W2008025550 cites W2166057591 @default.
- W2008025550 cites W2168903887 @default.
- W2008025550 cites W2317137640 @default.
- W2008025550 doi "https://doi.org/10.1111/j.1600-0404.1999.tb00738.x" @default.
- W2008025550 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10478585" @default.
- W2008025550 hasPublicationYear "2009" @default.
- W2008025550 type Work @default.
- W2008025550 sameAs 2008025550 @default.
- W2008025550 citedByCount "8" @default.
- W2008025550 countsByYear W20080255502012 @default.
- W2008025550 countsByYear W20080255502017 @default.
- W2008025550 countsByYear W20080255502019 @default.
- W2008025550 countsByYear W20080255502020 @default.
- W2008025550 countsByYear W20080255502021 @default.
- W2008025550 crossrefType "journal-article" @default.
- W2008025550 hasAuthorship W2008025550A5021485368 @default.
- W2008025550 hasAuthorship W2008025550A5073217377 @default.
- W2008025550 hasAuthorship W2008025550A5086689881 @default.
- W2008025550 hasConcept C104317684 @default.
- W2008025550 hasConcept C135763542 @default.
- W2008025550 hasConcept C142724271 @default.
- W2008025550 hasConcept C149737253 @default.
- W2008025550 hasConcept C166252455 @default.
- W2008025550 hasConcept C180754005 @default.
- W2008025550 hasConcept C197754878 @default.
- W2008025550 hasConcept C2778817970 @default.
- W2008025550 hasConcept C2779134260 @default.
- W2008025550 hasConcept C2780647506 @default.
- W2008025550 hasConcept C35605836 @default.
- W2008025550 hasConcept C37463918 @default.
- W2008025550 hasConcept C54355233 @default.
- W2008025550 hasConcept C71924100 @default.
- W2008025550 hasConcept C86803240 @default.
- W2008025550 hasConceptScore W2008025550C104317684 @default.
- W2008025550 hasConceptScore W2008025550C135763542 @default.
- W2008025550 hasConceptScore W2008025550C142724271 @default.
- W2008025550 hasConceptScore W2008025550C149737253 @default.
- W2008025550 hasConceptScore W2008025550C166252455 @default.
- W2008025550 hasConceptScore W2008025550C180754005 @default.
- W2008025550 hasConceptScore W2008025550C197754878 @default.
- W2008025550 hasConceptScore W2008025550C2778817970 @default.
- W2008025550 hasConceptScore W2008025550C2779134260 @default.
- W2008025550 hasConceptScore W2008025550C2780647506 @default.
- W2008025550 hasConceptScore W2008025550C35605836 @default.
- W2008025550 hasConceptScore W2008025550C37463918 @default.
- W2008025550 hasConceptScore W2008025550C54355233 @default.
- W2008025550 hasConceptScore W2008025550C71924100 @default.
- W2008025550 hasConceptScore W2008025550C86803240 @default.
- W2008025550 hasIssue "3" @default.
- W2008025550 hasLocation W20080255501 @default.
- W2008025550 hasLocation W20080255502 @default.
- W2008025550 hasOpenAccess W2008025550 @default.
- W2008025550 hasPrimaryLocation W20080255501 @default.
- W2008025550 hasRelatedWork W1989887426 @default.
- W2008025550 hasRelatedWork W1995194052 @default.
- W2008025550 hasRelatedWork W2022929933 @default.
- W2008025550 hasRelatedWork W2029588242 @default.
- W2008025550 hasRelatedWork W2068033436 @default.
- W2008025550 hasRelatedWork W2071887209 @default.
- W2008025550 hasRelatedWork W2166057591 @default.
- W2008025550 hasRelatedWork W2776931086 @default.
- W2008025550 hasRelatedWork W2911485752 @default.
- W2008025550 hasRelatedWork W4285586820 @default.
- W2008025550 hasVolume "100" @default.
- W2008025550 isParatext "false" @default.
- W2008025550 isRetracted "false" @default.
- W2008025550 magId "2008025550" @default.
- W2008025550 workType "article" @default.