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- W2008043010 abstract "RNA-binding proteins play central roles in cellularmetabolism. They are responsible for the transcription,processing, localization, transport, and translation ofRNA; accordingly, they are essential for controlled cellgrowth and proper organismal development. Severalfamilies of RNA-binding proteins have been identifiedthat share common RNA-binding motifs. These includethe RRM (RNA recognition motif) proteins that primarily bind to single-stranded RNA (ssRNA) (Shamoo et al.1995), the zinc finger motif proteins that bind to duplexedDNA as well as double-stranded RNA (dsRNA) (Finertyand Bass 1997, 1999; Yang et al. 1999), and the dsRNAbinding motif (dsRBM) proteins that bind to duplexedand highly structured RNA (Fierro-Monti and Mathews2000). The dsRBM is characterized by an α–β–β–β–αstructure that is involved in binding to dsRNA and alsoserves as a protein–protein interaction motif..." @default.
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- W2008043010 date "2001-01-01" @default.
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- W2008043010 title "Double-stranded RNA-binding Proteins and the Control of Protein Synthesis and Cell Growth" @default.
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- W2008043010 doi "https://doi.org/10.1101/sqb.2001.66.485" @default.
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