FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008061223> ?p ?o ?g. }

• W2008061223 endingPage "281" @default.
• W2008061223 startingPage "273" @default.
• W2008061223 abstract "Polyphenolic compounds were examined for their effects on suppressing adipocyte differentiation in 3T3-L1 cells. Most polyphenolic compounds inhibited adipocyte development from 3T3-L1 cells to some extent. Among them, rutin was the most effective in suppressing adipocyte differentiation in a dosage dependant manner. Activity of glycerol-3-phosphate dehydrogenase (GPDH), which has a central position in lipogenesis in adipose cells, was also decreased by rutin addition at the induction stage. RT-PCR results demonstrated that mRNA expression of adipogenic transcription factors such as peroxisome proliferator-activated receptor-γ (PPARγ) and CCAAT/enhancer binding protein-α (C/EBPα) in 3T3-L1 cells were remarkably down regulated by rutin treatment. For further investigation on anti-adipogenic activities of rutin, it was orally administered (25 and 50 mg/kg b.w/daily) with high-fat diet (64.4% of total calories as fat) to C57BL/6 mice. Body weight gains were less in high-fat diet + rutin fed groups (HFR) than high-fat diet alone fed group (HF) after 4 weeks. Total cholesterol contents in blood were significantly lower in HFR groups. When mRNA expressions of PPARγ and C/EBPα in hepatocytes were compared between the control HF and HFR groups, their expressions in hepatocytes of HFR groups were significantly suppressed. These results indicate that rutin inhibits adipogenic development in pre-adipocytes and hepatocytes by down regulating expressions of key adipogenic transcription factors." @default.
• W2008061223 created "2016-06-24" @default.
• W2008061223 creator A5005154519 @default.
• W2008061223 creator A5018731769 @default.
• W2008061223 creator A5078379907 @default.
• W2008061223 creator A5083050578 @default.
• W2008061223 date "2006-01-01" @default.
• W2008061223 modified "2023-09-25" @default.
• W2008061223 title "Anti-adipogenic activity of rutin in 3T3-L1 cells and mice fed with high-fat diet" @default.
• W2008061223 cites W1775749144 @default.
• W2008061223 cites W1907219612 @default.
• W2008061223 cites W1963805273 @default.
• W2008061223 cites W1971553494 @default.
• W2008061223 cites W1974156337 @default.
• W2008061223 cites W1974627368 @default.
• W2008061223 cites W1978840408 @default.
• W2008061223 cites W1982676267 @default.
• W2008061223 cites W1993102144 @default.
• W2008061223 cites W1994212260 @default.
• W2008061223 cites W2000223380 @default.
• W2008061223 cites W2002163749 @default.
• W2008061223 cites W2013534510 @default.
• W2008061223 cites W2029732176 @default.
• W2008061223 cites W2053619526 @default.
• W2008061223 cites W2061144747 @default.
• W2008061223 cites W2061728606 @default.
• W2008061223 cites W2071866695 @default.
• W2008061223 cites W2077483002 @default.
• W2008061223 cites W2083456175 @default.
• W2008061223 cites W2094115400 @default.
• W2008061223 cites W2106384759 @default.
• W2008061223 cites W2124578454 @default.
• W2008061223 cites W2148574282 @default.
• W2008061223 cites W2150557496 @default.
• W2008061223 cites W2167949935 @default.
• W2008061223 cites W2172256092 @default.
• W2008061223 cites W2173681478 @default.
• W2008061223 cites W4244189832 @default.
• W2008061223 doi "https://doi.org/10.1002/biof.5520260405" @default.
• W2008061223 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17119273" @default.
• W2008061223 hasPublicationYear "2006" @default.
• W2008061223 type Work @default.
• W2008061223 sameAs 2008061223 @default.
• W2008061223 citedByCount "94" @default.
• W2008061223 countsByYear W20080612232012 @default.
• W2008061223 countsByYear W20080612232013 @default.
• W2008061223 countsByYear W20080612232014 @default.
• W2008061223 countsByYear W20080612232015 @default.
• W2008061223 countsByYear W20080612232016 @default.
• W2008061223 countsByYear W20080612232017 @default.
• W2008061223 countsByYear W20080612232018 @default.
• W2008061223 countsByYear W20080612232019 @default.
• W2008061223 countsByYear W20080612232020 @default.
• W2008061223 countsByYear W20080612232021 @default.
• W2008061223 countsByYear W20080612232022 @default.
• W2008061223 countsByYear W20080612232023 @default.
• W2008061223 crossrefType "journal-article" @default.
• W2008061223 hasAuthorship W2008061223A5005154519 @default.
• W2008061223 hasAuthorship W2008061223A5018731769 @default.
• W2008061223 hasAuthorship W2008061223A5078379907 @default.
• W2008061223 hasAuthorship W2008061223A5083050578 @default.
• W2008061223 hasConcept C122927707 @default.
• W2008061223 hasConcept C126322002 @default.
• W2008061223 hasConcept C134018914 @default.
• W2008061223 hasConcept C141359234 @default.
• W2008061223 hasConcept C142536801 @default.
• W2008061223 hasConcept C171089720 @default.
• W2008061223 hasConcept C185592680 @default.
• W2008061223 hasConcept C2775963812 @default.
• W2008061223 hasConcept C2776175234 @default.
• W2008061223 hasConcept C2778004101 @default.
• W2008061223 hasConcept C55493867 @default.
• W2008061223 hasConcept C71924100 @default.
• W2008061223 hasConcept C86803240 @default.
• W2008061223 hasConceptScore W2008061223C122927707 @default.
• W2008061223 hasConceptScore W2008061223C126322002 @default.
• W2008061223 hasConceptScore W2008061223C134018914 @default.
• W2008061223 hasConceptScore W2008061223C141359234 @default.
• W2008061223 hasConceptScore W2008061223C142536801 @default.
• W2008061223 hasConceptScore W2008061223C171089720 @default.
• W2008061223 hasConceptScore W2008061223C185592680 @default.
• W2008061223 hasConceptScore W2008061223C2775963812 @default.
• W2008061223 hasConceptScore W2008061223C2776175234 @default.
• W2008061223 hasConceptScore W2008061223C2778004101 @default.
• W2008061223 hasConceptScore W2008061223C55493867 @default.
• W2008061223 hasConceptScore W2008061223C71924100 @default.
• W2008061223 hasConceptScore W2008061223C86803240 @default.
• W2008061223 hasIssue "4" @default.
• W2008061223 hasLocation W20080612231 @default.
• W2008061223 hasLocation W20080612232 @default.
• W2008061223 hasOpenAccess W2008061223 @default.
• W2008061223 hasPrimaryLocation W20080612231 @default.
• W2008061223 hasRelatedWork W1592691368 @default.
• W2008061223 hasRelatedWork W1951732046 @default.
• W2008061223 hasRelatedWork W2008061223 @default.
• W2008061223 hasRelatedWork W2015867011 @default.
• W2008061223 hasRelatedWork W2017606817 @default.
• W2008061223 hasRelatedWork W2051376891 @default.

• next