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- W2008073080 abstract "Mice whose IgH alleles are engineered to encode two distinct antibody heavy (H) chains generate a normal-sized B cell compartment in which most cells stably express the two heavy chains. This demonstrates that “toxicity” of bi-allelic H chain expression and cell- autonomous mechanisms of silencing in-frame IgH gene rearrangements do not significantly contribute to allelic exclusion at the IgH locus. Notwithstanding, the stability of the various engineered IgH loci during B cell development in the bone marrow differed substantially from each other." @default.
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- W2008073080 date "1997-03-01" @default.
- W2008073080 modified "2023-09-28" @default.
- W2008073080 title "B Cell Development under the Condition of Allelic Inclusion" @default.
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- W2008073080 doi "https://doi.org/10.1016/s1074-7613(00)80325-8" @default.
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