Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008082012> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2008082012 endingPage "117" @default.
- W2008082012 startingPage "113" @default.
- W2008082012 abstract "Local recurrence of well-differentiated thyroid carcinoma has a reported mortality approaching 50%. The University of Kentucky experience was reviewed to determine whether aggressive surveillance and treatment with reoperation and/or I-131 ablation increased survival following recurrence. Records of 66 consecutive patients with well-differentiated thyroid carcinoma treated at the University of Kentucky Medical Center (1980–1989) were reviewed. Forty-nine cases of papillary carcinoma and 17 cases of follicular carcinoma were studied; median follow-up was 68 months. At presentation, patients with follicular carcinoma were older (48 versus 35 years; P < 0.05) and more frequently had metastatic disease (17% versus 2%, P < 0.05). Fifty-eight (88%) patients were alive and diseasefree at last follow-up. Fifteen patients (24%) had developed recurrent disease; median time to recurrence was 24 months. Multivariate regression examined the variables of age, sex, histology, tumor size, cervical adenopathy, capsular and vascular invasion, multicentricity, and surgical procedure. While distant metastases affected actuarial survival, no factor independently predicted local recurrence. In six patients with local recurrence, nonpalpable disease was detected by I-131 scan. All were treated with ablation and remain disease-free (mean follow-up 42 months). Eight patients with local recurrence presented with palpable lesions; seven underwent surgery. While two patients developed repeated local recurrences, the other five remain diseasefree (mean follow-up 52 months). Early detection and aggressive treatment of local recurrence improve survival in patients with well-differentiated thyroid carcinoma. To facilitate use of I-131, we advise total thyroidectomy for patients with welldifferentiated thyroid carcinoma." @default.
- W2008082012 created "2016-06-24" @default.
- W2008082012 creator A5013997983 @default.
- W2008082012 creator A5034195468 @default.
- W2008082012 creator A5038334502 @default.
- W2008082012 creator A5071647593 @default.
- W2008082012 creator A5077606846 @default.
- W2008082012 creator A5079635279 @default.
- W2008082012 date "1992-02-01" @default.
- W2008082012 modified "2023-09-23" @default.
- W2008082012 title "Management of local recurrence in well-differentiated thyroid carcinoma" @default.
- W2008082012 cites W1423114918 @default.
- W2008082012 cites W1597263227 @default.
- W2008082012 cites W1979300931 @default.
- W2008082012 cites W2010903978 @default.
- W2008082012 cites W2019626818 @default.
- W2008082012 cites W2038391733 @default.
- W2008082012 cites W2066187373 @default.
- W2008082012 cites W2073432420 @default.
- W2008082012 cites W2087457590 @default.
- W2008082012 cites W2091809548 @default.
- W2008082012 cites W2097384041 @default.
- W2008082012 cites W2098579257 @default.
- W2008082012 cites W2136505409 @default.
- W2008082012 cites W2413709964 @default.
- W2008082012 cites W2416364339 @default.
- W2008082012 cites W2999879745 @default.
- W2008082012 doi "https://doi.org/10.1016/0022-4804(92)90289-c" @default.
- W2008082012 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1740931" @default.
- W2008082012 hasPublicationYear "1992" @default.
- W2008082012 type Work @default.
- W2008082012 sameAs 2008082012 @default.
- W2008082012 citedByCount "18" @default.
- W2008082012 countsByYear W20080820122020 @default.
- W2008082012 crossrefType "journal-article" @default.
- W2008082012 hasAuthorship W2008082012A5013997983 @default.
- W2008082012 hasAuthorship W2008082012A5034195468 @default.
- W2008082012 hasAuthorship W2008082012A5038334502 @default.
- W2008082012 hasAuthorship W2008082012A5071647593 @default.
- W2008082012 hasAuthorship W2008082012A5077606846 @default.
- W2008082012 hasAuthorship W2008082012A5079635279 @default.
- W2008082012 hasConcept C126322002 @default.
- W2008082012 hasConcept C141071460 @default.
- W2008082012 hasConcept C195910791 @default.
- W2008082012 hasConcept C2777074255 @default.
- W2008082012 hasConcept C2777546739 @default.
- W2008082012 hasConcept C2779761222 @default.
- W2008082012 hasConcept C2993294228 @default.
- W2008082012 hasConcept C526584372 @default.
- W2008082012 hasConcept C71924100 @default.
- W2008082012 hasConceptScore W2008082012C126322002 @default.
- W2008082012 hasConceptScore W2008082012C141071460 @default.
- W2008082012 hasConceptScore W2008082012C195910791 @default.
- W2008082012 hasConceptScore W2008082012C2777074255 @default.
- W2008082012 hasConceptScore W2008082012C2777546739 @default.
- W2008082012 hasConceptScore W2008082012C2779761222 @default.
- W2008082012 hasConceptScore W2008082012C2993294228 @default.
- W2008082012 hasConceptScore W2008082012C526584372 @default.
- W2008082012 hasConceptScore W2008082012C71924100 @default.
- W2008082012 hasIssue "2" @default.
- W2008082012 hasLocation W20080820121 @default.
- W2008082012 hasLocation W20080820122 @default.
- W2008082012 hasOpenAccess W2008082012 @default.
- W2008082012 hasPrimaryLocation W20080820121 @default.
- W2008082012 hasRelatedWork W1929014698 @default.
- W2008082012 hasRelatedWork W1958345765 @default.
- W2008082012 hasRelatedWork W1970100166 @default.
- W2008082012 hasRelatedWork W2002215244 @default.
- W2008082012 hasRelatedWork W2085144152 @default.
- W2008082012 hasRelatedWork W2085244961 @default.
- W2008082012 hasRelatedWork W2319110013 @default.
- W2008082012 hasRelatedWork W2581922924 @default.
- W2008082012 hasRelatedWork W4282912927 @default.
- W2008082012 hasRelatedWork W4307276876 @default.
- W2008082012 hasVolume "52" @default.
- W2008082012 isParatext "false" @default.
- W2008082012 isRetracted "false" @default.
- W2008082012 magId "2008082012" @default.
- W2008082012 workType "article" @default.