FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008082181> ?p ?o ?g. }

• W2008082181 endingPage "S284" @default.
• W2008082181 startingPage "S283" @default.
• W2008082181 abstract "In most IVF programs, the morphological characteristics of the embryos are evaluated on the day of transfer and the embryos with the highest morphological scores are transferred. We compared two different embryo-scoring methods, D.3 vs. GES and found no differences in either the pregnancy rates or the implantation rates with either scoring method. Embryos expressing a high concentration of sHLA-G, have been shown to improve implantation rates. The aim of this study was to compare pregnancy rates and implantation rates when embryos are selected based on a single D.3 score vs. a GES score plus sHLA-G expression. Prospective randomized pilot study Patients undergoing ICSI, were randomized to receive embryos based on a single D.3 score or a GES score plus sHLA-G expression. The D.3 score was based on the number of blastomeres and the extent of fragmentation on D.3. The GES score was based on the alignment of the nucleoli at the 2-pronuclear (2PN) stage, early cleavage (ie cleaved or not cleaved at 26 hours after ICSI), the number of blastomeres and the extent of fragmentation on D.3. sHLA-G expression was monitored by assaying the culture media. Embryos were cultured individually in 50 μl droplets of P-1 medium (Irvine Scientific, Santa Ana, CA) for 44-46 hours and moved to Complete Blastocyst Medium (Irvine Scientific, Santa Ana, CA). At this point, the P-1 culture media drops were collected and assayed for sHLA-G, using an enzyme-linked immunosorbent sandwich (ELISA) assay. Patients were treated by the same physician. A human derived gonadotropin (Bravelle; Ferring Pharmaceuticals Inc, Suffern, NY) was used in all patients. The same embryologist did the scoring of all embryos. Embryos with the highest D.3 score or GES score and expressing sHLA-G within a range of 0.190 ± 0.006 (mean ± SD) were transferred on D.3. Analysis of variance (ANOVA) and Chi-square tests were used for comparisons. Statistical significance was achieved if P<0.05. Of the 35 patients studied, 21 received embryos based only on a D. 3 score. The remaining 14 patients received embryos based on a GES score plus sHLA-G expression. The results are shown in the table below. Data expressed as means ± SD or % Tabled 1 Continuing pregnancy rates and implantation rates tended to be higher (p=0.05) when embryos were selected based on a GES score plus sHLA-G expression. We believe, pregnancy rates and implantation rates in IVF patients could be improved by selecting embryos based on a GES score plus sHLA-G expression." @default.
• W2008082181 created "2016-06-24" @default.
• W2008082181 creator A5028306045 @default.
• W2008082181 creator A5038961156 @default.
• W2008082181 date "2005-09-01" @default.
• W2008082181 modified "2023-09-30" @default.
• W2008082181 title "A Prospective Randomized Pilot Study Comparing Pregnancy Rates and Implantation Rates When Embryos are Selected Based on a Single day 3 (D.3) Score vs. a Graduated Embryo Score (GES) Plus Soluble Human Leukocyte Antigen-G (sHLA-G) Expression" @default.
• W2008082181 doi "https://doi.org/10.1016/j.fertnstert.2005.07.737" @default.
• W2008082181 hasPublicationYear "2005" @default.
• W2008082181 type Work @default.
• W2008082181 sameAs 2008082181 @default.
• W2008082181 citedByCount "0" @default.
• W2008082181 crossrefType "journal-article" @default.
• W2008082181 hasAuthorship W2008082181A5028306045 @default.
• W2008082181 hasAuthorship W2008082181A5038961156 @default.
• W2008082181 hasBestOaLocation W20080821811 @default.
• W2008082181 hasConcept C126322002 @default.
• W2008082181 hasConcept C160099875 @default.
• W2008082181 hasConcept C16685009 @default.
• W2008082181 hasConcept C168563851 @default.
• W2008082181 hasConcept C196843134 @default.
• W2008082181 hasConcept C2776537878 @default.
• W2008082181 hasConcept C2778177303 @default.
• W2008082181 hasConcept C2779234561 @default.
• W2008082181 hasConcept C2779335785 @default.
• W2008082181 hasConcept C29456083 @default.
• W2008082181 hasConcept C54355233 @default.
• W2008082181 hasConcept C68760520 @default.
• W2008082181 hasConcept C71924100 @default.
• W2008082181 hasConcept C86803240 @default.
• W2008082181 hasConcept C87073359 @default.
• W2008082181 hasConceptScore W2008082181C126322002 @default.
• W2008082181 hasConceptScore W2008082181C160099875 @default.
• W2008082181 hasConceptScore W2008082181C16685009 @default.
• W2008082181 hasConceptScore W2008082181C168563851 @default.
• W2008082181 hasConceptScore W2008082181C196843134 @default.
• W2008082181 hasConceptScore W2008082181C2776537878 @default.
• W2008082181 hasConceptScore W2008082181C2778177303 @default.
• W2008082181 hasConceptScore W2008082181C2779234561 @default.
• W2008082181 hasConceptScore W2008082181C2779335785 @default.
• W2008082181 hasConceptScore W2008082181C29456083 @default.
• W2008082181 hasConceptScore W2008082181C54355233 @default.
• W2008082181 hasConceptScore W2008082181C68760520 @default.
• W2008082181 hasConceptScore W2008082181C71924100 @default.
• W2008082181 hasConceptScore W2008082181C86803240 @default.
• W2008082181 hasConceptScore W2008082181C87073359 @default.
• W2008082181 hasLocation W20080821811 @default.
• W2008082181 hasOpenAccess W2008082181 @default.
• W2008082181 hasPrimaryLocation W20080821811 @default.
• W2008082181 hasRelatedWork W1603060409 @default.
• W2008082181 hasRelatedWork W1661322724 @default.
• W2008082181 hasRelatedWork W1964863752 @default.
• W2008082181 hasRelatedWork W2016587339 @default.
• W2008082181 hasRelatedWork W2038646023 @default.
• W2008082181 hasRelatedWork W2077796134 @default.
• W2008082181 hasRelatedWork W2129824844 @default.
• W2008082181 hasRelatedWork W2150935013 @default.
• W2008082181 hasRelatedWork W2396699723 @default.
• W2008082181 hasRelatedWork W2190912993 @default.
• W2008082181 hasVolume "84" @default.
• W2008082181 isParatext "false" @default.
• W2008082181 isRetracted "false" @default.
• W2008082181 magId "2008082181" @default.
• W2008082181 workType "article" @default.