Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008088030> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2008088030 endingPage "2579" @default.
- W2008088030 startingPage "2573" @default.
- W2008088030 abstract "Ethylenebisdithiocarbamates (EBDCs) are widely used fungicides. Ethylenethiourea (ETU), the main metabolite and also a contaminant in the commercially available products, is of major toxicological concern. In this study, a method using liquid chromatography/triple quadrupole mass spectrometry (LC/MS/MS) is described for the analysis of ETU in human urine after a single-step extractive derivatization using pentafluorobenzyl bromide (PFBBr). Analysis was carried out using selected reaction monitoring (SRM) in the positive ion mode. Quantification of ETU was performed using [(2)H(4)]-labeled ETU as internal standard (IS). The limit of detection (LOD) was determined to 0.05 ng/mL. The method was linear in the range 0.1-54 ng/mL urine and had a within-run precision of 3-5%. The between-run precision was determined at an average urine level of 2 and 10 ng/mL urine and found to be 9%. The inter-batch precision was 6%. To validate ETU as a biomarker of exposure, the method was applied in a human experimental oral exposure to the commercial fungicide Ridomil Gold, containing 64% mancozeb and 4.5% ETU. Two healthy volunteers received 8.9 microg/kg body weight (b.w.) Ridomil Gold in a single oral dose followed by urine sampling for 104 h post-exposure. The elimination half-life of ETU was estimated to 17-23 h." @default.
- W2008088030 created "2016-06-24" @default.
- W2008088030 creator A5004251967 @default.
- W2008088030 creator A5071384333 @default.
- W2008088030 creator A5077053822 @default.
- W2008088030 creator A5085977745 @default.
- W2008088030 date "2008-07-24" @default.
- W2008088030 modified "2023-10-16" @default.
- W2008088030 title "Analysis of ethylenethiourea as a biomarker in human urine using liquid chromatography/triple quadrupole mass spectrometry" @default.
- W2008088030 cites W1965060487 @default.
- W2008088030 cites W1974149498 @default.
- W2008088030 cites W1976916490 @default.
- W2008088030 cites W1980852410 @default.
- W2008088030 cites W2014897596 @default.
- W2008088030 cites W2018561123 @default.
- W2008088030 cites W2020310293 @default.
- W2008088030 cites W2042546690 @default.
- W2008088030 cites W2055877588 @default.
- W2008088030 cites W2059069686 @default.
- W2008088030 cites W2071244311 @default.
- W2008088030 cites W2074619987 @default.
- W2008088030 cites W2089601744 @default.
- W2008088030 cites W2102372180 @default.
- W2008088030 cites W2118385936 @default.
- W2008088030 cites W2133302351 @default.
- W2008088030 cites W2133512508 @default.
- W2008088030 cites W2166650531 @default.
- W2008088030 cites W2740125212 @default.
- W2008088030 cites W4234099295 @default.
- W2008088030 doi "https://doi.org/10.1002/rcm.3647" @default.
- W2008088030 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18651716" @default.
- W2008088030 hasPublicationYear "2008" @default.
- W2008088030 type Work @default.
- W2008088030 sameAs 2008088030 @default.
- W2008088030 citedByCount "20" @default.
- W2008088030 countsByYear W20080880302012 @default.
- W2008088030 countsByYear W20080880302013 @default.
- W2008088030 countsByYear W20080880302014 @default.
- W2008088030 countsByYear W20080880302015 @default.
- W2008088030 countsByYear W20080880302016 @default.
- W2008088030 countsByYear W20080880302017 @default.
- W2008088030 countsByYear W20080880302018 @default.
- W2008088030 countsByYear W20080880302020 @default.
- W2008088030 countsByYear W20080880302021 @default.
- W2008088030 countsByYear W20080880302023 @default.
- W2008088030 crossrefType "journal-article" @default.
- W2008088030 hasAuthorship W2008088030A5004251967 @default.
- W2008088030 hasAuthorship W2008088030A5071384333 @default.
- W2008088030 hasAuthorship W2008088030A5077053822 @default.
- W2008088030 hasAuthorship W2008088030A5085977745 @default.
- W2008088030 hasConcept C119128265 @default.
- W2008088030 hasConcept C162356407 @default.
- W2008088030 hasConcept C172493649 @default.
- W2008088030 hasConcept C185592680 @default.
- W2008088030 hasConcept C2776923573 @default.
- W2008088030 hasConcept C2777477808 @default.
- W2008088030 hasConcept C2780026642 @default.
- W2008088030 hasConcept C31827203 @default.
- W2008088030 hasConcept C43617362 @default.
- W2008088030 hasConcept C55493867 @default.
- W2008088030 hasConcept C64489805 @default.
- W2008088030 hasConcept C71043704 @default.
- W2008088030 hasConceptScore W2008088030C119128265 @default.
- W2008088030 hasConceptScore W2008088030C162356407 @default.
- W2008088030 hasConceptScore W2008088030C172493649 @default.
- W2008088030 hasConceptScore W2008088030C185592680 @default.
- W2008088030 hasConceptScore W2008088030C2776923573 @default.
- W2008088030 hasConceptScore W2008088030C2777477808 @default.
- W2008088030 hasConceptScore W2008088030C2780026642 @default.
- W2008088030 hasConceptScore W2008088030C31827203 @default.
- W2008088030 hasConceptScore W2008088030C43617362 @default.
- W2008088030 hasConceptScore W2008088030C55493867 @default.
- W2008088030 hasConceptScore W2008088030C64489805 @default.
- W2008088030 hasConceptScore W2008088030C71043704 @default.
- W2008088030 hasIssue "16" @default.
- W2008088030 hasLocation W20080880301 @default.
- W2008088030 hasLocation W20080880302 @default.
- W2008088030 hasOpenAccess W2008088030 @default.
- W2008088030 hasPrimaryLocation W20080880301 @default.
- W2008088030 hasRelatedWork W1973119017 @default.
- W2008088030 hasRelatedWork W1987886540 @default.
- W2008088030 hasRelatedWork W2003174742 @default.
- W2008088030 hasRelatedWork W2017325659 @default.
- W2008088030 hasRelatedWork W2043672469 @default.
- W2008088030 hasRelatedWork W2062375825 @default.
- W2008088030 hasRelatedWork W2164176383 @default.
- W2008088030 hasRelatedWork W2916126509 @default.
- W2008088030 hasRelatedWork W2958581523 @default.
- W2008088030 hasRelatedWork W2999309814 @default.
- W2008088030 hasVolume "22" @default.
- W2008088030 isParatext "false" @default.
- W2008088030 isRetracted "false" @default.
- W2008088030 magId "2008088030" @default.
- W2008088030 workType "article" @default.