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- W2008145309 abstract "A rapid and specific method for the determination of bleomycin A2 is described. A 50-microliter aliquot of 20% trichloroacetic acid was added to 200 microliter of plasma. The sample was vortexed and centrifuged, and 50 microliter of the clear supernate was injected into a liquid chromatograph equipped with a microparticulate reversed-phase column and a fixed wavelength detector. Elution was carried out using methanol-acetonitrile-0.0085 M heptanesulfonic acid-acetic acid. A linear calibration curve was found in the 0.05-5 microgram/ml range with an estimated precision of +/-6% (CV). Preliminary pharmacokinetic data in the rabbit also are reported." @default.
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- W2008145309 title "Rapid High-Performance Liquid Chromatographic Determination of Bleomycin A2 in Plasma" @default.
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- W2008145309 doi "https://doi.org/10.1002/jps.2600680228" @default.
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