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- W2008160904 abstract "Abstract It has been suggested that the cis conformation about the TrpNMeNle amide bond is important in conferring high affinity and selectivity to CCK-B receptor ligands. Substitution of the cis amide bond mimic Trpψ(CH4)Nle into the peptide Gly-Trp-N-(Me)Nle-Asp-PheNH2 causes it to lose activity, suggesting that other structural effects of N-(Me)Nle incorporation may be important for high affinity selectivity for the CCK-B receptor." @default.
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- W2008160904 date "1993-10-01" @default.
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- W2008160904 title "Tryptophan-norleucine 1,5-disubstituted tetrazoles as cis peptide bond mimics: Investigation of the bioactive conformation of a potent and selective peptide for the cholecystokinin-B receptor" @default.
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- W2008160904 doi "https://doi.org/10.1016/s0960-894x(01)81005-2" @default.
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