FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008162316> ?p ?o ?g. }

• W2008162316 abstract "Abstract Cells infected with Rous sarcoma virus (RSV) produce three classes of virus-specific mRNAs—one that has the size of the viral genome and two that are smaller than the genome. We have explored the mechanisms by which these viral mRNAs are produced. The site for initiation of viral RNA synthesis was located by using irradiation with ultraviolet light to inactivate transcription in infected cells. The metabolism of viral RNA was elucidated by the use of glucosamine to effect satisfactory pulse-chase experiments. We conclude that transcription from the RSV provirus initiates at or near the nucleotide that encodes the 5′ terminus of the viral genome. The primary transcript is subsequently processed to generate the subgenomic mRNAs, which appear independently of each other between 15 and 45 min after the synthesis of their precursor. Viral RNA has several distinctive fates: ca. 35% remains in the cell in the form of the genomic length mRNA; 10–20% takes the form fo subgenomic mRNAs; and the remaining 50% disappears from the cell, presumably because of export as viral genome (but perhaps also as a consequence of degradation within the cell). Our data provide a functional definition for the initiation of viral RNA synthesis and conform to the results of recent structural studies that have identified a possible “promoter site” near the ends of the RSV provirus." @default.
• W2008162316 created "2016-06-24" @default.
• W2008162316 creator A5023586836 @default.
• W2008162316 creator A5032924224 @default.
• W2008162316 creator A5089138950 @default.
• W2008162316 date "1981-07-01" @default.
• W2008162316 modified "2023-09-24" @default.
• W2008162316 title "The genesis of rous sarcoma virus messenger RNAs" @default.
• W2008162316 cites W113309747 @default.
• W2008162316 cites W1513007123 @default.
• W2008162316 cites W1658188469 @default.
• W2008162316 cites W1678091602 @default.
• W2008162316 cites W1698885819 @default.
• W2008162316 cites W1701072163 @default.
• W2008162316 cites W1732105733 @default.
• W2008162316 cites W1792996135 @default.
• W2008162316 cites W1832749657 @default.
• W2008162316 cites W1908127430 @default.
• W2008162316 cites W1967318154 @default.
• W2008162316 cites W1968095512 @default.
• W2008162316 cites W1969705974 @default.
• W2008162316 cites W1971495757 @default.
• W2008162316 cites W1979011571 @default.
• W2008162316 cites W1983767419 @default.
• W2008162316 cites W1984724155 @default.
• W2008162316 cites W1990849144 @default.
• W2008162316 cites W1992893612 @default.
• W2008162316 cites W1996948250 @default.
• W2008162316 cites W1997664029 @default.
• W2008162316 cites W2007089478 @default.
• W2008162316 cites W2007297734 @default.
• W2008162316 cites W2025675183 @default.
• W2008162316 cites W2030022491 @default.
• W2008162316 cites W2031985588 @default.
• W2008162316 cites W2046502861 @default.
• W2008162316 cites W2052226697 @default.
• W2008162316 cites W2053185521 @default.
• W2008162316 cites W2071190126 @default.
• W2008162316 cites W2071238487 @default.
• W2008162316 cites W2072946352 @default.
• W2008162316 cites W2076099663 @default.
• W2008162316 cites W2082516898 @default.
• W2008162316 cites W2086125483 @default.
• W2008162316 cites W2089337451 @default.
• W2008162316 cites W2089423740 @default.
• W2008162316 cites W2093182117 @default.
• W2008162316 cites W2114805139 @default.
• W2008162316 cites W2153486810 @default.
• W2008162316 cites W2154456113 @default.
• W2008162316 cites W2179320341 @default.
• W2008162316 cites W4245966595 @default.
• W2008162316 doi "https://doi.org/10.1016/0042-6822(81)90316-0" @default.
• W2008162316 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6266148" @default.
• W2008162316 hasPublicationYear "1981" @default.
• W2008162316 type Work @default.
• W2008162316 sameAs 2008162316 @default.
• W2008162316 citedByCount "16" @default.
• W2008162316 countsByYear W20081623162020 @default.
• W2008162316 crossrefType "journal-article" @default.
• W2008162316 hasAuthorship W2008162316A5023586836 @default.
• W2008162316 hasAuthorship W2008162316A5032924224 @default.
• W2008162316 hasAuthorship W2008162316A5089138950 @default.
• W2008162316 hasConcept C102906071 @default.
• W2008162316 hasConcept C104317684 @default.
• W2008162316 hasConcept C105580179 @default.
• W2008162316 hasConcept C138885662 @default.
• W2008162316 hasConcept C141231307 @default.
• W2008162316 hasConcept C153911025 @default.
• W2008162316 hasConcept C159047783 @default.
• W2008162316 hasConcept C179926584 @default.
• W2008162316 hasConcept C189819185 @default.
• W2008162316 hasConcept C2522874641 @default.
• W2008162316 hasConcept C2777441520 @default.
• W2008162316 hasConcept C41895202 @default.
• W2008162316 hasConcept C54355233 @default.
• W2008162316 hasConcept C67705224 @default.
• W2008162316 hasConcept C86803240 @default.
• W2008162316 hasConcept C95444343 @default.
• W2008162316 hasConceptScore W2008162316C102906071 @default.
• W2008162316 hasConceptScore W2008162316C104317684 @default.
• W2008162316 hasConceptScore W2008162316C105580179 @default.
• W2008162316 hasConceptScore W2008162316C138885662 @default.
• W2008162316 hasConceptScore W2008162316C141231307 @default.
• W2008162316 hasConceptScore W2008162316C153911025 @default.
• W2008162316 hasConceptScore W2008162316C159047783 @default.
• W2008162316 hasConceptScore W2008162316C179926584 @default.
• W2008162316 hasConceptScore W2008162316C189819185 @default.
• W2008162316 hasConceptScore W2008162316C2522874641 @default.
• W2008162316 hasConceptScore W2008162316C2777441520 @default.
• W2008162316 hasConceptScore W2008162316C41895202 @default.
• W2008162316 hasConceptScore W2008162316C54355233 @default.
• W2008162316 hasConceptScore W2008162316C67705224 @default.
• W2008162316 hasConceptScore W2008162316C86803240 @default.
• W2008162316 hasConceptScore W2008162316C95444343 @default.
• W2008162316 hasLocation W20081623161 @default.
• W2008162316 hasLocation W20081623162 @default.
• W2008162316 hasOpenAccess W2008162316 @default.
• W2008162316 hasPrimaryLocation W20081623161 @default.
• W2008162316 hasRelatedWork W1487857142 @default.
• W2008162316 hasRelatedWork W1959977791 @default.

• next