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- W2008164023 abstract "Nine new thiazachalcone-based drugs, compounds 1–9, were prepared and fully characterized. The configurations of the photochemical-dimerization products 7–9 were rationalized by semi-empirical calculations. Both the experimental data and the theoretical calculations showed that the δ-truxinic acid type dimer is the most stable isomer of all. All compounds were tested for their antibacterial and antifungal activities. The N-alkylated congeners 4–6 showed strong antimicrobial activities against various bacteria and a yeast-like fungus. The MIC and MBC values were as low as 0.1 μg/ml. All the compounds were active against the Gram-positive bacterium Staphylococcus aureus." @default.
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- W2008164023 date "2007-08-01" @default.
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- W2008164023 title "Synthesis, Configuration, and Antimicrobial Properties of Novel Substituted and Cyclized ‘2′,3″-Thiazachalcones’" @default.
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- W2008164023 doi "https://doi.org/10.1002/hlca.200790154" @default.
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