Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008164090> ?p ?o ?g. }
- W2008164090 endingPage "e28497" @default.
- W2008164090 startingPage "e28497" @default.
- W2008164090 abstract "Natural Killer Group 2 member D (NKG2D) activating receptor, present on the surface of various immune cells, plays an important role in activating the anticancer immune response by their interaction with stress-inducible NKG2D ligands (NKG2DL) on transformed cells. However, cancer cells have developed numerous mechanisms to evade the immune system via the downregulation of NKG2DL from the cell surface, including the release of NKG2DL from the cell surface in a soluble form. Here, we review the mechanisms involved in the production of soluble NKG2DL (sNKG2DL) and the potential therapeutic strategies aiming to block the release of these immunosuppressive ligands. Therapeutically enabling the NKG2D-NKG2DL interaction would promote immunorecognition of malignant cells, thus abrogating disease progression." @default.
- W2008164090 created "2016-06-24" @default.
- W2008164090 creator A5032408537 @default.
- W2008164090 creator A5076862422 @default.
- W2008164090 creator A5091591327 @default.
- W2008164090 date "2014-04-01" @default.
- W2008164090 modified "2023-09-27" @default.
- W2008164090 title "Secretory pathways generating immunosuppressive NKG2D ligands: New targets for therapeutic intervention" @default.
- W2008164090 cites W1681870720 @default.
- W2008164090 cites W1894510512 @default.
- W2008164090 cites W1922785475 @default.
- W2008164090 cites W1942558899 @default.
- W2008164090 cites W1963940744 @default.
- W2008164090 cites W1964444828 @default.
- W2008164090 cites W1969090863 @default.
- W2008164090 cites W1973851782 @default.
- W2008164090 cites W1978088258 @default.
- W2008164090 cites W1978496119 @default.
- W2008164090 cites W1979991238 @default.
- W2008164090 cites W1983146096 @default.
- W2008164090 cites W1985576417 @default.
- W2008164090 cites W1995385753 @default.
- W2008164090 cites W1998662458 @default.
- W2008164090 cites W2000200130 @default.
- W2008164090 cites W2002286451 @default.
- W2008164090 cites W2002863353 @default.
- W2008164090 cites W2004746660 @default.
- W2008164090 cites W2006350053 @default.
- W2008164090 cites W2011770999 @default.
- W2008164090 cites W2014176736 @default.
- W2008164090 cites W2014349052 @default.
- W2008164090 cites W2019463432 @default.
- W2008164090 cites W2020404158 @default.
- W2008164090 cites W2024292448 @default.
- W2008164090 cites W2026895645 @default.
- W2008164090 cites W2028695120 @default.
- W2008164090 cites W2032541432 @default.
- W2008164090 cites W2035744694 @default.
- W2008164090 cites W2042854868 @default.
- W2008164090 cites W2045070144 @default.
- W2008164090 cites W2046701977 @default.
- W2008164090 cites W2050658289 @default.
- W2008164090 cites W2051491397 @default.
- W2008164090 cites W2052095307 @default.
- W2008164090 cites W2056219816 @default.
- W2008164090 cites W2061793037 @default.
- W2008164090 cites W2070154805 @default.
- W2008164090 cites W2072648073 @default.
- W2008164090 cites W2076172880 @default.
- W2008164090 cites W2076757423 @default.
- W2008164090 cites W2078990740 @default.
- W2008164090 cites W2085478834 @default.
- W2008164090 cites W2085600319 @default.
- W2008164090 cites W2086739969 @default.
- W2008164090 cites W2089522070 @default.
- W2008164090 cites W2092285890 @default.
- W2008164090 cites W2096245789 @default.
- W2008164090 cites W2100599030 @default.
- W2008164090 cites W2106677006 @default.
- W2008164090 cites W2107756707 @default.
- W2008164090 cites W2117269475 @default.
- W2008164090 cites W2124164679 @default.
- W2008164090 cites W2126078977 @default.
- W2008164090 cites W2127211080 @default.
- W2008164090 cites W2129673110 @default.
- W2008164090 cites W2138872728 @default.
- W2008164090 cites W2139309246 @default.
- W2008164090 cites W2140159527 @default.
- W2008164090 cites W2143241095 @default.
- W2008164090 cites W2143561528 @default.
- W2008164090 cites W2146783950 @default.
- W2008164090 cites W2147443000 @default.
- W2008164090 cites W2152487395 @default.
- W2008164090 cites W2155602568 @default.
- W2008164090 cites W2155797075 @default.
- W2008164090 cites W2158080596 @default.
- W2008164090 cites W2162826156 @default.
- W2008164090 cites W2164294039 @default.
- W2008164090 cites W2166970460 @default.
- W2008164090 cites W2171471266 @default.
- W2008164090 doi "https://doi.org/10.4161/onci.28497" @default.
- W2008164090 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4063154" @default.
- W2008164090 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25050215" @default.
- W2008164090 hasPublicationYear "2014" @default.
- W2008164090 type Work @default.
- W2008164090 sameAs 2008164090 @default.
- W2008164090 citedByCount "64" @default.
- W2008164090 countsByYear W20081640902014 @default.
- W2008164090 countsByYear W20081640902015 @default.
- W2008164090 countsByYear W20081640902016 @default.
- W2008164090 countsByYear W20081640902017 @default.
- W2008164090 countsByYear W20081640902018 @default.
- W2008164090 countsByYear W20081640902019 @default.
- W2008164090 countsByYear W20081640902020 @default.
- W2008164090 countsByYear W20081640902021 @default.
- W2008164090 countsByYear W20081640902022 @default.
- W2008164090 countsByYear W20081640902023 @default.
- W2008164090 crossrefType "journal-article" @default.