Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008173894> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2008173894 endingPage "9" @default.
- W2008173894 startingPage "68" @default.
- W2008173894 abstract "The management of hemorrhages in patients with strong inhibitors to factor VIII continues to challenge our ingenuity. No therapy stops all hemorrhages in all patients. We live with the possibility of uncontrollable bleeding. New treatment modalities are welcomed with eager hopefulness. Prothrombin complex concentrates (PCCs), usually used to treat hemophilia B (factor IX deficiency), shorten the partial thromboplastin time when added in vitro to plasma containing inhibitor to factor VIII. On the basis of this observation, PCCs were first tried in patients with critical hemorrhages in the early 1970s, with dramatic success in several instances. Purposely activated PCCs—including Autoplex, United States, and FEIBA, Austria (anti-inhibitor coagulant complex)—have a greater ability in vitro to bypass the need for factor VIII than ordinary PCCs, such as Konȳne or Proplex (factor IX complex), but all PCC products have been used extensively in patients with inhibitors. Evaluation of the efficacy of PCCs is difficult." @default.
- W2008173894 created "2016-06-24" @default.
- W2008173894 creator A5088954638 @default.
- W2008173894 date "1984-01-06" @default.
- W2008173894 modified "2023-09-23" @default.
- W2008173894 title "Prothrombin complex concentrates and inhibitors. A reappraisal." @default.
- W2008173894 cites W1571639926 @default.
- W2008173894 cites W2128025612 @default.
- W2008173894 cites W2321411638 @default.
- W2008173894 cites W2403444710 @default.
- W2008173894 cites W2734698134 @default.
- W2008173894 cites W34531854 @default.
- W2008173894 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6418899" @default.
- W2008173894 hasPublicationYear "1984" @default.
- W2008173894 type Work @default.
- W2008173894 sameAs 2008173894 @default.
- W2008173894 citedByCount "0" @default.
- W2008173894 crossrefType "journal-article" @default.
- W2008173894 hasAuthorship W2008173894A5088954638 @default.
- W2008173894 hasConcept C126322002 @default.
- W2008173894 hasConcept C141071460 @default.
- W2008173894 hasConcept C177713679 @default.
- W2008173894 hasConcept C186738567 @default.
- W2008173894 hasConcept C2776301958 @default.
- W2008173894 hasConcept C2777091921 @default.
- W2008173894 hasConcept C2778261982 @default.
- W2008173894 hasConcept C2778382381 @default.
- W2008173894 hasConcept C2779161974 @default.
- W2008173894 hasConcept C2779936836 @default.
- W2008173894 hasConcept C2781221834 @default.
- W2008173894 hasConcept C2908626413 @default.
- W2008173894 hasConcept C2909974469 @default.
- W2008173894 hasConcept C71924100 @default.
- W2008173894 hasConceptScore W2008173894C126322002 @default.
- W2008173894 hasConceptScore W2008173894C141071460 @default.
- W2008173894 hasConceptScore W2008173894C177713679 @default.
- W2008173894 hasConceptScore W2008173894C186738567 @default.
- W2008173894 hasConceptScore W2008173894C2776301958 @default.
- W2008173894 hasConceptScore W2008173894C2777091921 @default.
- W2008173894 hasConceptScore W2008173894C2778261982 @default.
- W2008173894 hasConceptScore W2008173894C2778382381 @default.
- W2008173894 hasConceptScore W2008173894C2779161974 @default.
- W2008173894 hasConceptScore W2008173894C2779936836 @default.
- W2008173894 hasConceptScore W2008173894C2781221834 @default.
- W2008173894 hasConceptScore W2008173894C2908626413 @default.
- W2008173894 hasConceptScore W2008173894C2909974469 @default.
- W2008173894 hasConceptScore W2008173894C71924100 @default.
- W2008173894 hasIssue "1" @default.
- W2008173894 hasLocation W20081738941 @default.
- W2008173894 hasOpenAccess W2008173894 @default.
- W2008173894 hasPrimaryLocation W20081738941 @default.
- W2008173894 hasRelatedWork W1493791357 @default.
- W2008173894 hasRelatedWork W1979894151 @default.
- W2008173894 hasRelatedWork W1998224120 @default.
- W2008173894 hasRelatedWork W2008173894 @default.
- W2008173894 hasRelatedWork W2017345748 @default.
- W2008173894 hasRelatedWork W2032036529 @default.
- W2008173894 hasRelatedWork W2408996892 @default.
- W2008173894 hasRelatedWork W2409417030 @default.
- W2008173894 hasRelatedWork W2419423938 @default.
- W2008173894 hasRelatedWork W94165806 @default.
- W2008173894 hasVolume "251" @default.
- W2008173894 isParatext "false" @default.
- W2008173894 isRetracted "false" @default.
- W2008173894 magId "2008173894" @default.
- W2008173894 workType "article" @default.