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• W2008200326 abstract "Over the last few years, much research has focused on determining the function of members of the cytosolic Nod-like receptor (NLR) family in terms of their triggers and the signaling pathways that they control. Members of this family include the NLRP proteins, which play a role in sensing both microbial and danger signals and triggering the caspase-1 dependent inflammasome, and the Nod subfamily characterized by proteins with a caspase-activating and recruitment domain (CARD) or a so-called 'X' domain. Nod1, Nod2, NLRX1 and NLRC5 are all members of this subfamily and in this review, we will focus on recent work that has shown the importance of these molecules in both pathogen sensing and regulation of innate and adaptive immunity." @default.
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• W2008200326 date "2011-02-01" @default.
• W2008200326 modified "2023-10-16" @default.
• W2008200326 title "What is new with Nods?" @default.
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• W2008200326 doi "https://doi.org/10.1016/j.coi.2010.12.003" @default.
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