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• W2008201503 abstract "Six azaphilones, monascin (1), ankaflavin (2), rubropunctatin (3), monascorburin (4), rubropunctamine (5), and monascorburamine (6), two furanoisophthalides, xanthomonasin A (7) and xanthomonasin B (8), and two amino acids, (+)-monascumic acid (9) and (−)-monascumic acid (10), isolated from the extracts of Monascus pilosus-fermented rice (red-mold rice) were evaluated for their inhibitory effects on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice, on the induction of Epstein−Barr virus early antigen (EBV-EA) by TPA in Raji cells, and on the activation of (±)-(E)-methyl-2[(E)-hydroxy-imino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor. Among the compounds tested, seven compounds (1−6 and 10) on TPA-induced inflammation, and six compounds (1, 3−5, 9, and 10) on EBV-EA activation, exhibited potent inhibitory effects. All of the compounds tested showed moderate inhibitory effects on NOR 1 activation. Keywords: Monascus pilosus; red-mold rice; azaphilones; furanoisophthalides; amino acids; TPA-induced ear edema; antitumor-promoter; Epstein−Barr virus early antigen" @default.
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• W2008201503 date "2005-01-14" @default.
• W2008201503 modified "2023-09-30" @default.
• W2008201503 title "Azaphilones, Furanoisophthalides, and Amino Acids from the Extracts of <i>Monascus pilosus</i>-Fermented Rice (Red-Mold Rice) and Their Chemopreventive Effects" @default.
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• W2008201503 doi "https://doi.org/10.1021/jf040199p" @default.
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