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- W2008221879 abstract "A new liquid-phase piezoelectric immunosensor (LP-PEIS), which can detect Schistosoma japonicum (Sj) circulating antigens (SjCAg) quantificationally, was developed.The IgG antibodies were purified from the sera of rabbits which had been infected or immunized by Sj and were immobilized on the surface of piezoelectric quartz crystal in LP-PEIS by staphylococcal protein A (SPA). It was used to detect SjCAg in sera of rabbits which had been infected by Sj in order to acquire some optimum conditions for detecting SjCAg. Finally, the LP-PEIS with optimum conditions was used to detect SjCAg in sera of patients who had been infected by Sj, and was compared with sandwich ELISA.A lot of optimum conditions of LP-PEIS for detecting SjCAg had been acquired. In the detection of patients' sera with acute Schistosomiasis, LP-PEIS has higher positive rate (100%) and lower false positive rate (3.0%) than sandwich ELISA (92.8%, 6.0%). However, there were no significant difference between LP-PEIS and sandwich ELISA.LP-PEIS can quantificationally detect SjCAg in patients' sera as well as sandwich ELISA." @default.
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- W2008221879 date "2011-09-01" @default.
- W2008221879 modified "2023-09-27" @default.
- W2008221879 title "A novel liquid-phase piezoelectric immunosensor for detecting Schistosoma japonicum circulating antigen" @default.
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- W2008221879 doi "https://doi.org/10.1016/j.parint.2011.05.001" @default.
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