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- W2008228646 abstract "The role of autonomic tone on antegrade atrioventricular nodal (AVN) conduction was assessed in 8 pts (7 f, 1 m, 52 ± 11 yrs) with common type AVN reentrant tachycardia (AVNRT) before and after radiofrequency current (RFC) ablation of the slow pathway (SP). AVN conduction curves and refractoriness (ref) were analyzed during baseline and following i.v. administration of propranolol (0.2 mg/kg) and atropine (0.04 mg/kg) before (day 1) and after RFC ablation (day 2). During pre-ablation baseline state, curves consistent with two antegrade AVN conduction pathways were observed in 4 pts and with three pathways in 3 pts. Autonomic blockade (AB) produced new dual patterns in 1 pt and annulled them in 2/7 pts, preventing from inducibility of AVNRT observed during baseline in 1; AVN ref was either unaffected (5 pts), markedly prolonged (2 pts) or shortened (1 pt), with nonpredictable changes of atrium-to-hissian (A-H) conduction interval curves. After RFC ablation, AVNRT inducibility was abolished in all pts and dual AVN physiology in all but 1 pt during baseline; ref of the fast pathway (FP) was reduced in 4n pts. AB after RFC exposed dual AVN physiology in another pt in whom also changes in AVN ref and AH interval curves were produced. Data from this study suggest that the electrophysiologic substrate of AVNRT is more complex than the one defined by a dual pathway. Pharmacologic AB may expose otherwise unrecognized dual AVN physiology without consistent ability of inducing AVNRT after RFC ablation. AVN ref and A-H conduction do not present predictable behavioural patterns in response to either AB and RFC applied to the posterior-inferior approach to the AV node." @default.
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- W2008228646 date "1995-02-01" @default.
- W2008228646 modified "2023-10-16" @default.
- W2008228646 title "976-13 Autonomic Effects on Nodal Conduction as Assessed Before and After Radiofrequency Current Ablation in Patients with Atrioventricular Nodal Reentrant Tachycardia" @default.
- W2008228646 doi "https://doi.org/10.1016/0735-1097(95)92520-f" @default.
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