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- W2008255195 abstract "An economical new process route has been developed for the large-scale synthesis of memantine hydrochloride (1) an anti-Alzheimer's drug. The procedure involves the conversion of 1,3-dimethyl adamantane (2) to formamide intermediate 8 as a key step, followed by hydrolysis to (1-amino-3,5-dimethyl adamantane) hydrochloride (1) in good yield." @default.
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- W2008255195 date "2007-02-15" @default.
- W2008255195 modified "2023-10-17" @default.
- W2008255195 title "An Improved Synthesis of Memantine Hydrochloride: Anti-Alzheimer's Drug" @default.
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- W2008255195 doi "https://doi.org/10.1021/op060246+" @default.
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