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- W2008258596 abstract "Abstract An efficient and practical method for the synthesis of indole as a key starting material for many useful chemicals is described. Using 2-nitrotoluene as starting material, hydroxymethylation with formaldehyde under alkaline conditions gave 2-(2-nitrophenyl)ethanol on a large scale. Raney Ni catalyst was used for both reduction of the nitro group as well as for the indole formation. The overall yield was 78% from 2-nitrotoluene." @default.
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- W2008258596 date "2011-07-15" @default.
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- W2008258596 title "Convenient and Scalable Process for the Preparation of Indole via Raney Nickel–Catalyzed Hydrogenation and Ring Closure" @default.
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- W2008258596 doi "https://doi.org/10.1080/00397911.2010.495828" @default.
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