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- W2008306513 abstract "A synthetic pathway to new acyclonucleoside phosphonates, as analogues of Adefovir, is described. The reduction of an acyclonucleoside β-ketophosphonate, readily available from the nucleobase and benzylacrylate, afforded a mixture of (R)- and (S)-β-hydroxyphosphonate derivatives which was resolved. The assignment of the absolute configuration was proposed on the basis of NMR studies and was supported by molecular modelling studies." @default.
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- W2008306513 date "2011-07-01" @default.
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- W2008306513 title "Synthesis of (R)- and (S)-β-hydroxyphosphonate acyclonucleosides: structural analogues of Adefovir (PMEA)" @default.
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- W2008306513 doi "https://doi.org/10.1016/j.tetasy.2011.08.010" @default.
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