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- W2008334995 abstract "Fine-needle aspiration (FNA) of cold thyroid nodules has become the first line diagnostic decision for electing which patients need surgeryIn order to improve FNA accuracy, the monoclonal antithyroperoxidase (TPO) antibody (MoAb47) was testedA total of 554 patients were included in this study and among them, 208 were referred to surgeryThe results of FNA compared to the final histological diagnosis revealed a sensitivity and a specificity of 94 and 55% respectively, while the sensitivity and specificity of TPO immunodetection on the same cases reached 98 and 83% respectivelyBy combining the two methods, the 3 false-negative of FNA and 60% of suspicious cytology corresponding to histological benign lesions were correctly identified by immunocytochemistry. With better results than FNA alone, TPO immunodetection with MoAb47 represents a useful adjunct to conventional cytology for selecting patients for surgery." @default.
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- W2008334995 date "1997-01-01" @default.
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- W2008334995 title "Evaluation of the Monoclonal Antibody Antithyroperoxidase MoAb47 in the Diagnostic Decision of Cold Thyroid Nodules by Fine-Needle Aspiration" @default.
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- W2008334995 doi "https://doi.org/10.1016/s0344-0338(97)80030-1" @default.
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