FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008335418> ?p ?o ?g. }

• W2008335418 endingPage "2179" @default.
• W2008335418 startingPage "2179" @default.
• W2008335418 abstract "Current climate issues and the ongoing depletion of oil reserves have led to increased attention for biobased production processes. Not only has the production of bio-energy gained interest, but also the production of biochemicals. Succinate is one of those biochemicals. In the presented work, the dicarboxylic acid transport system of Escherichia coli was modified to enhance production of succinate, a highly attractive chemical building block. The engineering comprised the elimination of succinate uptake and the overexpression of succinate export. However, succinate export in Escherichia coli is normally only active under anaerobic conditions and import only under aerobic conditions. Therefore, the gene responsible for succinate import, dctA, was knocked out and the gene coding for succinate export, dcuC, was overexpressed with a constitutive artificial promoter. In the applied batch cultivations, these modifications increased succinate yield and specific production rate more than 50% in a ΔsdhAΔsdhB background (0.16 C-mole/C-mole glucose and 0.17 C-mole/C-mole biomass/h, respectively), but also revealed alternative succinate import proteins, YdjN and YbhI. Mutations in the genes coding for these proteins led to increased growth rates and specific production rates, however, they did not increase succinate yield (e.g. the deletion of ybhI resulted in a growth rate of 0.54 h−1 and a specific production rate of 0.23 C-mole/C-mole biomass/h)." @default.
• W2008335418 created "2016-06-24" @default.
• W2008335418 creator A5006454718 @default.
• W2008335418 creator A5013310583 @default.
• W2008335418 creator A5015580659 @default.
• W2008335418 creator A5018398571 @default.
• W2008335418 creator A5039688066 @default.
• W2008335418 creator A5047263552 @default.
• W2008335418 creator A5072298237 @default.
• W2008335418 creator A5074016096 @default.
• W2008335418 creator A5076225859 @default.
• W2008335418 creator A5090214575 @default.
• W2008335418 date "2011-01-01" @default.
• W2008335418 modified "2023-10-16" @default.
• W2008335418 title "Influence of C4-dicarboxylic acid transporters on succinate production" @default.
• W2008335418 cites W1479945046 @default.
• W2008335418 cites W1660421813 @default.
• W2008335418 cites W1963584517 @default.
• W2008335418 cites W1974506452 @default.
• W2008335418 cites W1975301430 @default.
• W2008335418 cites W1993154270 @default.
• W2008335418 cites W2002605655 @default.
• W2008335418 cites W2035567172 @default.
• W2008335418 cites W2058658881 @default.
• W2008335418 cites W2069271002 @default.
• W2008335418 cites W2090436685 @default.
• W2008335418 cites W2095993386 @default.
• W2008335418 cites W2113613985 @default.
• W2008335418 cites W2116137883 @default.
• W2008335418 cites W2130381741 @default.
• W2008335418 cites W2144944670 @default.
• W2008335418 cites W2148395120 @default.
• W2008335418 cites W2154402996 @default.
• W2008335418 cites W2158714788 @default.
• W2008335418 cites W2172234039 @default.
• W2008335418 cites W2783507843 @default.
• W2008335418 cites W4239300697 @default.
• W2008335418 doi "https://doi.org/10.1039/c1gc15369b" @default.
• W2008335418 hasPublicationYear "2011" @default.
• W2008335418 type Work @default.
• W2008335418 sameAs 2008335418 @default.
• W2008335418 citedByCount "11" @default.
• W2008335418 countsByYear W20083354182013 @default.
• W2008335418 countsByYear W20083354182014 @default.
• W2008335418 countsByYear W20083354182015 @default.
• W2008335418 countsByYear W20083354182016 @default.
• W2008335418 countsByYear W20083354182017 @default.
• W2008335418 countsByYear W20083354182020 @default.
• W2008335418 countsByYear W20083354182022 @default.
• W2008335418 crossrefType "journal-article" @default.
• W2008335418 hasAuthorship W2008335418A5006454718 @default.
• W2008335418 hasAuthorship W2008335418A5013310583 @default.
• W2008335418 hasAuthorship W2008335418A5015580659 @default.
• W2008335418 hasAuthorship W2008335418A5018398571 @default.
• W2008335418 hasAuthorship W2008335418A5039688066 @default.
• W2008335418 hasAuthorship W2008335418A5047263552 @default.
• W2008335418 hasAuthorship W2008335418A5072298237 @default.
• W2008335418 hasAuthorship W2008335418A5074016096 @default.
• W2008335418 hasAuthorship W2008335418A5076225859 @default.
• W2008335418 hasAuthorship W2008335418A5090214575 @default.
• W2008335418 hasConcept C104317684 @default.
• W2008335418 hasConcept C124815738 @default.
• W2008335418 hasConcept C134121241 @default.
• W2008335418 hasConcept C181199279 @default.
• W2008335418 hasConcept C185592680 @default.
• W2008335418 hasConcept C191897082 @default.
• W2008335418 hasConcept C192562407 @default.
• W2008335418 hasConcept C2779620337 @default.
• W2008335418 hasConcept C2781041046 @default.
• W2008335418 hasConcept C2781330172 @default.
• W2008335418 hasConcept C547475151 @default.
• W2008335418 hasConcept C55493867 @default.
• W2008335418 hasConcept C62231903 @default.
• W2008335418 hasConcept C86803240 @default.
• W2008335418 hasConceptScore W2008335418C104317684 @default.
• W2008335418 hasConceptScore W2008335418C124815738 @default.
• W2008335418 hasConceptScore W2008335418C134121241 @default.
• W2008335418 hasConceptScore W2008335418C181199279 @default.
• W2008335418 hasConceptScore W2008335418C185592680 @default.
• W2008335418 hasConceptScore W2008335418C191897082 @default.
• W2008335418 hasConceptScore W2008335418C192562407 @default.
• W2008335418 hasConceptScore W2008335418C2779620337 @default.
• W2008335418 hasConceptScore W2008335418C2781041046 @default.
• W2008335418 hasConceptScore W2008335418C2781330172 @default.
• W2008335418 hasConceptScore W2008335418C547475151 @default.
• W2008335418 hasConceptScore W2008335418C55493867 @default.
• W2008335418 hasConceptScore W2008335418C62231903 @default.
• W2008335418 hasConceptScore W2008335418C86803240 @default.
• W2008335418 hasIssue "8" @default.
• W2008335418 hasLocation W20083354181 @default.
• W2008335418 hasOpenAccess W2008335418 @default.
• W2008335418 hasPrimaryLocation W20083354181 @default.
• W2008335418 hasRelatedWork W1561175926 @default.
• W2008335418 hasRelatedWork W1866236445 @default.
• W2008335418 hasRelatedWork W1985615521 @default.
• W2008335418 hasRelatedWork W2008335418 @default.
• W2008335418 hasRelatedWork W2048827223 @default.
• W2008335418 hasRelatedWork W2141898595 @default.

• next