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• W2008358536 abstract "Polyaniline (PANI) is considered as one of the most fascinating conductive polymers in fabricating enzyme-based biosensors. Nevertheless, to improve both sensitivity and stability of the PANI-modified biosensor has been and continues to be a technical challenge. In this study, we have electrochemically synthesized the PANI film on a platinum (Pt) electrode and then used this electrode to construct a horseradish peroxidase (HRP)-based biosensor for the detection of hydrogen peroxide (H2O2). The electrochemical and structural properties of electrodes were characterized with scanning electron microscopy (SEM), thermogravimetric analysis (TGA), Fourier-transform infrared (FTIR) spectrophotometer, and cyclic voltammetry (CV). It was interestingly found that the PANI film synthesized in the presence of bovine serum albumin (BSA) has provided the electrode with enhanced sensitivity and excellent stability. Our results suggested that the embedded BSA might serve as an initial template for aniline polymerization and stabilized the microstructure of the PANI film significantly. The constructed HRP/PANI(BSA)/Pt electrode also exhibited a fine linear correlation with H2O2 concentration. This approach by implanted BSA was useful for improving the sensitivity and stability of PANI-modified biosensor." @default.
• W2008358536 created "2016-06-24" @default.
• W2008358536 creator A5004753011 @default.
• W2008358536 creator A5052450062 @default.
• W2008358536 date "2008-01-18" @default.
• W2008358536 modified "2023-09-26" @default.
• W2008358536 title "Enhancing the sensitivity and stability of HRP/PANI/Pt electrode by implanted bovine serum albumin" @default.
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• W2008358536 doi "https://doi.org/10.1016/j.bios.2007.08.014" @default.
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