Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008391213> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2008391213 endingPage "452" @default.
- W2008391213 startingPage "447" @default.
- W2008391213 abstract "Sarcoidosis and hypersensitivity pneumonitis (HP) are two granulomatous pulmonary diseases, the former of unknown cause and the latter with known etiology. To compare these diseases, we practiced bronchoalveolar lavage on 16 patients with sarcoidosis, 6 with HP, 10 healthy nonsmokers, and 10 smokers with chronic bronchitis. Lymphocyte subpopulations were evaluated by four membrane markers: (1) The total cell count was very high in patients with HP compared with those with sarcoidosis and with healthy subjects. (2) The proportion of lymphocytes was higher in patients with HP than in those with sarcoidosis (P less than 0.02) and also higher in patients with sarcoidosis than in healthy subjects (P less than 0.001). (3) There were only a small number of B cells and of Fc-receptor bearing cells. (4) The lymphocytes identified by our techniques were mainly T cells in sarcoidosis and HP (68.4 +/- 3.5 percent and 76.8 +/- 3.6 percent, respectively), but the proportion of active E-rosette-forming cells was higher in sarcoidosis than in HP (28.1 +/- 2.5 percent vs 9.8 +/- 1.5 percent) and higher in patients with HP than in healthy subjects. These studies suggest that: (1) these two granulomatoses may be differentiated by this method, which might also be used for other pulmonary angiitis and granulomas; (2) cell-mediated immune phenomena play a major role in the pathogenesis of sarcoidosis, and conversely the finding of low active E-rosette proportions in HP limits the role of delayed-type hypersensitivity; and (3) the exact role of immunologic activation of bronchopulmonary macrophages, presenting antigen to T cells, for instance, must be evaluated." @default.
- W2008391213 created "2016-06-24" @default.
- W2008391213 creator A5001668256 @default.
- W2008391213 creator A5059816096 @default.
- W2008391213 creator A5075112000 @default.
- W2008391213 creator A5075387555 @default.
- W2008391213 creator A5087096460 @default.
- W2008391213 date "1981-10-01" @default.
- W2008391213 modified "2023-09-25" @default.
- W2008391213 title "Lymphocyte Subpopulations in Bronchoalveolar Lavages of Patients with Sarcoidosis and Hypersensitivity Pneumonitis" @default.
- W2008391213 cites W1532910452 @default.
- W2008391213 cites W1545192347 @default.
- W2008391213 cites W1576505312 @default.
- W2008391213 cites W1970668509 @default.
- W2008391213 cites W1977949904 @default.
- W2008391213 cites W1979897514 @default.
- W2008391213 cites W1992248996 @default.
- W2008391213 cites W2010734236 @default.
- W2008391213 cites W2012652405 @default.
- W2008391213 cites W2022708259 @default.
- W2008391213 cites W2029027998 @default.
- W2008391213 cites W2043068531 @default.
- W2008391213 cites W2051863245 @default.
- W2008391213 cites W2058067808 @default.
- W2008391213 cites W2059952658 @default.
- W2008391213 cites W2068948874 @default.
- W2008391213 cites W2089908314 @default.
- W2008391213 cites W2140504861 @default.
- W2008391213 cites W4253267429 @default.
- W2008391213 doi "https://doi.org/10.1378/chest.80.4.447" @default.
- W2008391213 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6974088" @default.
- W2008391213 hasPublicationYear "1981" @default.
- W2008391213 type Work @default.
- W2008391213 sameAs 2008391213 @default.
- W2008391213 citedByCount "66" @default.
- W2008391213 countsByYear W20083912132012 @default.
- W2008391213 countsByYear W20083912132013 @default.
- W2008391213 countsByYear W20083912132017 @default.
- W2008391213 countsByYear W20083912132019 @default.
- W2008391213 countsByYear W20083912132020 @default.
- W2008391213 countsByYear W20083912132021 @default.
- W2008391213 countsByYear W20083912132022 @default.
- W2008391213 crossrefType "journal-article" @default.
- W2008391213 hasAuthorship W2008391213A5001668256 @default.
- W2008391213 hasAuthorship W2008391213A5059816096 @default.
- W2008391213 hasAuthorship W2008391213A5075112000 @default.
- W2008391213 hasAuthorship W2008391213A5075387555 @default.
- W2008391213 hasAuthorship W2008391213A5087096460 @default.
- W2008391213 hasConcept C126322002 @default.
- W2008391213 hasConcept C137627325 @default.
- W2008391213 hasConcept C142724271 @default.
- W2008391213 hasConcept C203014093 @default.
- W2008391213 hasConcept C2777134676 @default.
- W2008391213 hasConcept C2777714996 @default.
- W2008391213 hasConcept C2777761686 @default.
- W2008391213 hasConcept C2777961210 @default.
- W2008391213 hasConcept C2780942790 @default.
- W2008391213 hasConcept C2781301800 @default.
- W2008391213 hasConcept C2992694001 @default.
- W2008391213 hasConcept C71924100 @default.
- W2008391213 hasConcept C8891405 @default.
- W2008391213 hasConceptScore W2008391213C126322002 @default.
- W2008391213 hasConceptScore W2008391213C137627325 @default.
- W2008391213 hasConceptScore W2008391213C142724271 @default.
- W2008391213 hasConceptScore W2008391213C203014093 @default.
- W2008391213 hasConceptScore W2008391213C2777134676 @default.
- W2008391213 hasConceptScore W2008391213C2777714996 @default.
- W2008391213 hasConceptScore W2008391213C2777761686 @default.
- W2008391213 hasConceptScore W2008391213C2777961210 @default.
- W2008391213 hasConceptScore W2008391213C2780942790 @default.
- W2008391213 hasConceptScore W2008391213C2781301800 @default.
- W2008391213 hasConceptScore W2008391213C2992694001 @default.
- W2008391213 hasConceptScore W2008391213C71924100 @default.
- W2008391213 hasConceptScore W2008391213C8891405 @default.
- W2008391213 hasIssue "4" @default.
- W2008391213 hasLocation W20083912131 @default.
- W2008391213 hasLocation W20083912132 @default.
- W2008391213 hasOpenAccess W2008391213 @default.
- W2008391213 hasPrimaryLocation W20083912131 @default.
- W2008391213 hasRelatedWork W2047371155 @default.
- W2008391213 hasRelatedWork W2076382315 @default.
- W2008391213 hasRelatedWork W2113465185 @default.
- W2008391213 hasRelatedWork W2121536949 @default.
- W2008391213 hasRelatedWork W2407761886 @default.
- W2008391213 hasRelatedWork W2410050790 @default.
- W2008391213 hasRelatedWork W2415138818 @default.
- W2008391213 hasRelatedWork W2462570999 @default.
- W2008391213 hasRelatedWork W3197693317 @default.
- W2008391213 hasRelatedWork W3095864423 @default.
- W2008391213 hasVolume "80" @default.
- W2008391213 isParatext "false" @default.
- W2008391213 isRetracted "false" @default.
- W2008391213 magId "2008391213" @default.
- W2008391213 workType "article" @default.