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• W2008403967 endingPage "1101" @default.
• W2008403967 startingPage "1089" @default.
• W2008403967 abstract "Ribose phosphates are either synthesized through the oxidative branch of the pentose phosphate pathway, or are supplied by nucleoside phosphorylases. The two main pentose phosphates, ribose-5-phosphate and ribose-1-phosphate, are readily interconverted by the action of phosphopentomutase. Ribose-5-phosphate is the direct precursor of 5-phosphoribosyl-1-pyrophosphate, for both de novo and ‘salvage’ synthesis of nucleotides. Phosphorolysis of deoxyribonucleosides is the main source of deoxyribose phosphates, which are interconvertible, through the action of phosphopentomutase. The pentose moiety of all nucleosides can serve as a carbon and energy source. During the past decade, extensive advances have been made in elucidating the pathways by which the pentose phosphates, arising from nucleoside phosphorolysis, are either recycled, without opening of their furanosidic ring, or catabolized as a carbon and energy source. We review herein the experimental knowledge on the molecular mechanisms by which (a) ribose-1-phosphate, produced by purine nucleoside phosphorylase acting catabolically, is either anabolized for pyrimidine salvage and 5-fluorouracil activation, with uridine phosphorylase acting anabolically, or recycled for nucleoside and base interconversion; (b) the nucleosides can be regarded, both in bacteria and in eukaryotic cells, as carriers of sugars, that are made available though the action of nucleoside phosphorylases. In bacteria, catabolism of nucleosides, when suitable carbon and energy sources are not available, is accomplished by a battery of nucleoside transporters and of inducible catabolic enzymes for purine and pyrimidine nucleosides and for pentose phosphates. In eukaryotic cells, the modulation of pentose phosphate production by nucleoside catabolism seems to be affected by developmental and physiological factors on enzyme levels." @default.
• W2008403967 created "2016-06-24" @default.
• W2008403967 creator A5029895526 @default.
• W2008403967 creator A5039831914 @default.
• W2008403967 creator A5050957257 @default.
• W2008403967 creator A5069200792 @default.
• W2008403967 creator A5072944073 @default.
• W2008403967 date "2006-03-01" @default.
• W2008403967 modified "2023-10-12" @default.
• W2008403967 title "Pentose phosphates in nucleoside interconversion and catabolism" @default.
• W2008403967 cites W110774903 @default.
• W2008403967 cites W1484210791 @default.
• W2008403967 cites W1494972817 @default.
• W2008403967 cites W1518450791 @default.
• W2008403967 cites W1536591983 @default.
• W2008403967 cites W1537919308 @default.
• W2008403967 cites W1560226854 @default.
• W2008403967 cites W1566297179 @default.
• W2008403967 cites W1578231679 @default.
• W2008403967 cites W1579051410 @default.
• W2008403967 cites W1581252490 @default.
• W2008403967 cites W1583495252 @default.
• W2008403967 cites W1585261002 @default.
• W2008403967 cites W1598878817 @default.
• W2008403967 cites W1687051724 @default.
• W2008403967 cites W1715374218 @default.
• W2008403967 cites W1828589360 @default.
• W2008403967 cites W1858588481 @default.
• W2008403967 cites W1869396122 @default.
• W2008403967 cites W1956368731 @default.
• W2008403967 cites W1963719931 @default.
• W2008403967 cites W1964891034 @default.
• W2008403967 cites W196604938 @default.
• W2008403967 cites W1967117412 @default.
• W2008403967 cites W1967471508 @default.
• W2008403967 cites W1968846280 @default.
• W2008403967 cites W1970775245 @default.
• W2008403967 cites W1978538541 @default.
• W2008403967 cites W1978845542 @default.
• W2008403967 cites W1978923910 @default.
• W2008403967 cites W1981253503 @default.
• W2008403967 cites W1985420286 @default.
• W2008403967 cites W1995288608 @default.
• W2008403967 cites W1997338257 @default.
• W2008403967 cites W1998163769 @default.
• W2008403967 cites W1999568267 @default.
• W2008403967 cites W2003009263 @default.
• W2008403967 cites W2003677194 @default.
• W2008403967 cites W2004978531 @default.
• W2008403967 cites W2005014046 @default.
• W2008403967 cites W2005285041 @default.
• W2008403967 cites W2006732267 @default.
• W2008403967 cites W2006979184 @default.
• W2008403967 cites W2012367667 @default.
• W2008403967 cites W2017297916 @default.
• W2008403967 cites W2023588802 @default.
• W2008403967 cites W2035913814 @default.
• W2008403967 cites W2035953077 @default.
• W2008403967 cites W2040048782 @default.
• W2008403967 cites W2040831406 @default.
• W2008403967 cites W2041307146 @default.
• W2008403967 cites W2043053368 @default.
• W2008403967 cites W2044150227 @default.
• W2008403967 cites W2045074917 @default.
• W2008403967 cites W2047541913 @default.
• W2008403967 cites W2049491919 @default.
• W2008403967 cites W2050701583 @default.
• W2008403967 cites W2051337665 @default.
• W2008403967 cites W2052395983 @default.
• W2008403967 cites W2054829814 @default.
• W2008403967 cites W2055482409 @default.
• W2008403967 cites W2059301686 @default.
• W2008403967 cites W2064276205 @default.
• W2008403967 cites W2067278087 @default.
• W2008403967 cites W2071043643 @default.
• W2008403967 cites W2072288452 @default.
• W2008403967 cites W2072618321 @default.
• W2008403967 cites W2074656054 @default.
• W2008403967 cites W2077892699 @default.
• W2008403967 cites W2084213291 @default.
• W2008403967 cites W2085946662 @default.
• W2008403967 cites W2087060205 @default.
• W2008403967 cites W2089627668 @default.
• W2008403967 cites W2091766109 @default.
• W2008403967 cites W2093287523 @default.
• W2008403967 cites W2094013133 @default.
• W2008403967 cites W2094319340 @default.
• W2008403967 cites W2094320682 @default.
• W2008403967 cites W2094810573 @default.
• W2008403967 cites W2097220183 @default.
• W2008403967 cites W2120647825 @default.
• W2008403967 cites W2123569104 @default.
• W2008403967 cites W2128307593 @default.
• W2008403967 cites W2132261231 @default.
• W2008403967 cites W2132745887 @default.
• W2008403967 cites W2140238053 @default.
• W2008403967 cites W2145265630 @default.
• W2008403967 cites W2146062832 @default.

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