FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008405764> ?p ?o ?g. }

• W2008405764 abstract "Osteocytes are considered as the major mechanosensory cells of the bone tissue that control the bone remodeling process. Since osteocytes are buried inside mineralized matrix, they maintain a strong communication network with other cells. Long dendritic processes of the osteocytes act as communication cables, conveying mechanical signals to the neighboring osteocytes and the cells on the bone surface; like osteoblasts and osteoclasts. Gap junctions and hemichannels formed by Connexin (Cx) 43 are observed to be involved in responding to the mechanical stimulus and in communicating the mechano-responsive biochemical signals. The contrast in the arrangement of the osteocyte cell body and the dendrites raises an important question of how these parts of the osteocyte respond to mechanical stimulation. We addressed this issue in our recent report through the stimulation of either osteocyte cell body or dendrites and our findings suggest that the osteocyte dendritic processes are sensitive to mechanical stimulation in comparison to the cell body. Most importantly, we observed that the dendritic processes are capable of conveying the mechanical signals to the cell body. Our findings also suggested that the glycocalyx surrounding the dendrites is required for sensing and conveying the mechanical signals. Degradation of the glycocalyx also leads to poor integrin attachment, thereby, affecting dendritic stiffness. These results suggest that the osteocyte dendritic processes are highly responsive towards mechanical stimulation and the glycocalyx surrounding the dendrites is critical in transducing these mechanical signals." @default.
• W2008405764 created "2016-06-24" @default.
• W2008405764 creator A5036136277 @default.
• W2008405764 creator A5050766937 @default.
• W2008405764 creator A5057355394 @default.
• W2008405764 date "2011-01-01" @default.
• W2008405764 modified "2023-10-12" @default.
• W2008405764 title "Dark horse in osteocyte biology: Glycocalyx around the dendrites is critical for osteocyte mechanosensing." @default.
• W2008405764 cites W13942825 @default.
• W2008405764 cites W1602919907 @default.
• W2008405764 cites W1973661281 @default.
• W2008405764 cites W1990524482 @default.
• W2008405764 cites W2002791970 @default.
• W2008405764 cites W2033496938 @default.
• W2008405764 cites W2037293839 @default.
• W2008405764 cites W2047136147 @default.
• W2008405764 cites W2062125301 @default.
• W2008405764 cites W2083920483 @default.
• W2008405764 cites W2093930926 @default.
• W2008405764 cites W2098274894 @default.
• W2008405764 cites W2101299206 @default.
• W2008405764 cites W2118055942 @default.
• W2008405764 cites W2131107390 @default.
• W2008405764 cites W2140454162 @default.
• W2008405764 cites W2151775473 @default.
• W2008405764 cites W2153479733 @default.
• W2008405764 cites W2163208284 @default.
• W2008405764 cites W2164319357 @default.
• W2008405764 cites W2403197741 @default.
• W2008405764 doi "https://doi.org/10.4161/cib.4.1.13646" @default.
• W2008405764 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3073269" @default.
• W2008405764 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21509177" @default.
• W2008405764 hasPublicationYear "2011" @default.
• W2008405764 type Work @default.
• W2008405764 sameAs 2008405764 @default.
• W2008405764 citedByCount "10" @default.
• W2008405764 countsByYear W20084057642012 @default.
• W2008405764 countsByYear W20084057642013 @default.
• W2008405764 countsByYear W20084057642016 @default.
• W2008405764 countsByYear W20084057642017 @default.
• W2008405764 countsByYear W20084057642019 @default.
• W2008405764 countsByYear W20084057642022 @default.
• W2008405764 crossrefType "journal-article" @default.
• W2008405764 hasAuthorship W2008405764A5036136277 @default.
• W2008405764 hasAuthorship W2008405764A5050766937 @default.
• W2008405764 hasAuthorship W2008405764A5057355394 @default.
• W2008405764 hasConcept C105702510 @default.
• W2008405764 hasConcept C169760540 @default.
• W2008405764 hasConcept C170493617 @default.
• W2008405764 hasConcept C181104049 @default.
• W2008405764 hasConcept C185592680 @default.
• W2008405764 hasConcept C202751555 @default.
• W2008405764 hasConcept C24998067 @default.
• W2008405764 hasConcept C2778260815 @default.
• W2008405764 hasConcept C2780098789 @default.
• W2008405764 hasConcept C2780973866 @default.
• W2008405764 hasConcept C2910319024 @default.
• W2008405764 hasConcept C4001165 @default.
• W2008405764 hasConcept C50254741 @default.
• W2008405764 hasConcept C55493867 @default.
• W2008405764 hasConcept C86803240 @default.
• W2008405764 hasConcept C95444343 @default.
• W2008405764 hasConceptScore W2008405764C105702510 @default.
• W2008405764 hasConceptScore W2008405764C169760540 @default.
• W2008405764 hasConceptScore W2008405764C170493617 @default.
• W2008405764 hasConceptScore W2008405764C181104049 @default.
• W2008405764 hasConceptScore W2008405764C185592680 @default.
• W2008405764 hasConceptScore W2008405764C202751555 @default.
• W2008405764 hasConceptScore W2008405764C24998067 @default.
• W2008405764 hasConceptScore W2008405764C2778260815 @default.
• W2008405764 hasConceptScore W2008405764C2780098789 @default.
• W2008405764 hasConceptScore W2008405764C2780973866 @default.
• W2008405764 hasConceptScore W2008405764C2910319024 @default.
• W2008405764 hasConceptScore W2008405764C4001165 @default.
• W2008405764 hasConceptScore W2008405764C50254741 @default.
• W2008405764 hasConceptScore W2008405764C55493867 @default.
• W2008405764 hasConceptScore W2008405764C86803240 @default.
• W2008405764 hasConceptScore W2008405764C95444343 @default.
• W2008405764 hasLocation W20084057641 @default.
• W2008405764 hasOpenAccess W2008405764 @default.
• W2008405764 hasPrimaryLocation W20084057641 @default.
• W2008405764 hasRelatedWork W1489922960 @default.
• W2008405764 hasRelatedWork W1972568078 @default.
• W2008405764 hasRelatedWork W2007225045 @default.
• W2008405764 hasRelatedWork W2019582558 @default.
• W2008405764 hasRelatedWork W2052139347 @default.
• W2008405764 hasRelatedWork W2066846288 @default.
• W2008405764 hasRelatedWork W2074494444 @default.
• W2008405764 hasRelatedWork W2082649337 @default.
• W2008405764 hasRelatedWork W2087571105 @default.
• W2008405764 hasRelatedWork W2104440688 @default.
• W2008405764 hasRelatedWork W2118055942 @default.
• W2008405764 hasRelatedWork W2131107390 @default.
• W2008405764 hasRelatedWork W2186092701 @default.
• W2008405764 hasRelatedWork W2415075562 @default.
• W2008405764 hasRelatedWork W2520744033 @default.
• W2008405764 hasRelatedWork W3033561017 @default.
• W2008405764 hasRelatedWork W3179307570 @default.
• W2008405764 hasRelatedWork W3187456374 @default.
• W2008405764 hasRelatedWork W55158486 @default.

• next