Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008432433> ?p ?o ?g. }
- W2008432433 endingPage "199" @default.
- W2008432433 startingPage "192" @default.
- W2008432433 abstract "Mucosal surfaces are important for the induction of immunity against influenza virus. In a murine intranasal immunization model, we demonstrated that the attenuated Shigella flexneri Δasd strain 15D, carrying a DNA construct encoding the influenza virus hemagglutinin (HA), induces protective immunity against a lethal respiratory challenge with influenza A/WSN/33. Influenza virus-specific IFN-γ T cells were detected among splenocytes, and anti-HA IgG was detected in serum post-immunization, albeit at low levels. Following influenza virus challenge, an accelerated anti-HA IgA antibody response was detected in bronchoalveolar lavage (BAL) washings from mice vaccinated with attenuated shigella containing the HA construct. These results suggest that S. flexneri Δasd strain 15D is a promising vector for mucosal DNA vaccine immunization against influenza virus and other mucosal pathogens." @default.
- W2008432433 created "2016-06-24" @default.
- W2008432433 creator A5011821997 @default.
- W2008432433 creator A5019724810 @default.
- W2008432433 creator A5063199727 @default.
- W2008432433 creator A5064519786 @default.
- W2008432433 creator A5064743793 @default.
- W2008432433 creator A5065326739 @default.
- W2008432433 creator A5077660812 @default.
- W2008432433 date "2004-08-01" @default.
- W2008432433 modified "2023-10-18" @default.
- W2008432433 title "Mucosal immunization with attenuated Shigella flexneri harboring an influenza hemagglutinin DNA vaccine protects mice against a lethal influenza challenge" @default.
- W2008432433 cites W1519185370 @default.
- W2008432433 cites W1792672594 @default.
- W2008432433 cites W1808202040 @default.
- W2008432433 cites W1808739935 @default.
- W2008432433 cites W1963716037 @default.
- W2008432433 cites W1969435176 @default.
- W2008432433 cites W1975544244 @default.
- W2008432433 cites W1979744805 @default.
- W2008432433 cites W1996982700 @default.
- W2008432433 cites W2002392006 @default.
- W2008432433 cites W2013184461 @default.
- W2008432433 cites W2016365074 @default.
- W2008432433 cites W2016767984 @default.
- W2008432433 cites W2017484306 @default.
- W2008432433 cites W2028065414 @default.
- W2008432433 cites W2038449290 @default.
- W2008432433 cites W2039200386 @default.
- W2008432433 cites W2063036448 @default.
- W2008432433 cites W2070426326 @default.
- W2008432433 cites W2072603042 @default.
- W2008432433 cites W2078290231 @default.
- W2008432433 cites W2095553197 @default.
- W2008432433 cites W2102070786 @default.
- W2008432433 cites W2104324781 @default.
- W2008432433 cites W2112349784 @default.
- W2008432433 cites W2113032412 @default.
- W2008432433 cites W2131974188 @default.
- W2008432433 cites W2137681090 @default.
- W2008432433 cites W2138239268 @default.
- W2008432433 cites W2139841187 @default.
- W2008432433 cites W2150630260 @default.
- W2008432433 cites W2154143591 @default.
- W2008432433 cites W2154145568 @default.
- W2008432433 cites W2155382443 @default.
- W2008432433 cites W2157441360 @default.
- W2008432433 cites W2159482672 @default.
- W2008432433 cites W2320976250 @default.
- W2008432433 doi "https://doi.org/10.1016/j.virol.2004.04.045" @default.
- W2008432433 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15246259" @default.
- W2008432433 hasPublicationYear "2004" @default.
- W2008432433 type Work @default.
- W2008432433 sameAs 2008432433 @default.
- W2008432433 citedByCount "22" @default.
- W2008432433 countsByYear W20084324332012 @default.
- W2008432433 countsByYear W20084324332014 @default.
- W2008432433 countsByYear W20084324332015 @default.
- W2008432433 countsByYear W20084324332017 @default.
- W2008432433 countsByYear W20084324332018 @default.
- W2008432433 countsByYear W20084324332021 @default.
- W2008432433 crossrefType "journal-article" @default.
- W2008432433 hasAuthorship W2008432433A5011821997 @default.
- W2008432433 hasAuthorship W2008432433A5019724810 @default.
- W2008432433 hasAuthorship W2008432433A5063199727 @default.
- W2008432433 hasAuthorship W2008432433A5064519786 @default.
- W2008432433 hasAuthorship W2008432433A5064743793 @default.
- W2008432433 hasAuthorship W2008432433A5065326739 @default.
- W2008432433 hasAuthorship W2008432433A5077660812 @default.
- W2008432433 hasConcept C104317684 @default.
- W2008432433 hasConcept C159047783 @default.
- W2008432433 hasConcept C159654299 @default.
- W2008432433 hasConcept C167508917 @default.
- W2008432433 hasConcept C203014093 @default.
- W2008432433 hasConcept C22070199 @default.
- W2008432433 hasConcept C2522874641 @default.
- W2008432433 hasConcept C2777546802 @default.
- W2008432433 hasConcept C2778692840 @default.
- W2008432433 hasConcept C2779341262 @default.
- W2008432433 hasConcept C2780801004 @default.
- W2008432433 hasConcept C2781217973 @default.
- W2008432433 hasConcept C54602769 @default.
- W2008432433 hasConcept C547475151 @default.
- W2008432433 hasConcept C55493867 @default.
- W2008432433 hasConcept C60987743 @default.
- W2008432433 hasConcept C86803240 @default.
- W2008432433 hasConcept C8891405 @default.
- W2008432433 hasConcept C89423630 @default.
- W2008432433 hasConceptScore W2008432433C104317684 @default.
- W2008432433 hasConceptScore W2008432433C159047783 @default.
- W2008432433 hasConceptScore W2008432433C159654299 @default.
- W2008432433 hasConceptScore W2008432433C167508917 @default.
- W2008432433 hasConceptScore W2008432433C203014093 @default.
- W2008432433 hasConceptScore W2008432433C22070199 @default.
- W2008432433 hasConceptScore W2008432433C2522874641 @default.
- W2008432433 hasConceptScore W2008432433C2777546802 @default.
- W2008432433 hasConceptScore W2008432433C2778692840 @default.
- W2008432433 hasConceptScore W2008432433C2779341262 @default.