FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008442981> ?p ?o ?g. }

• W2008442981 endingPage "285" @default.
• W2008442981 startingPage "276" @default.
• W2008442981 abstract "NO and H2S are gaseous signaling molecules that modulate smooth muscle motility. We aimed to identify expressions of enzymes that catalyze H2S and NO generation in mouse gastric smooth muscle, and determine relationships between endogenous H2S and NO in regulation of smooth muscle motility. Western blotting and immunocytochemistry methods were used to track expressions of neuronal nitric oxide synthase (nNOS), endothelial nitric oxide synthase (eNOS), cystathionine β-synthase (CBS) and cystathionine γ-lyase (CSE) in gastric smooth muscles. Smooth muscle motility was recorded by isometric force transducers. cGMP production was measured by a specific radioimmunoassay. We found that CBS, CSE, eNOS, and nNOS were all expressed in mice gastric antral smooth muscle tissues, and in cultured gastric antral smooth muscle cells. AOAA significantly inhibited smooth muscle contractions in the gastric antrum, which was significantly recovered by NaHS, while PAG had no significant effect. l-NAME enhanced contractions. NaHS at low concentrations increased basal tension but decreased it at high concentrations. SNP significantly inhibited the contractions, which could be recovered by NaHS both in the absence and presence of CuSO4. ODQ did not block NaHS-induced excitatory effect, while IBMX partially blocked this effect. cGMP production in smooth muscle was significantly increased by SNP but was not affected by NaHS. All these results suggest that endogenous H2S and NO appear to play opposite roles in regulating gastric motility and their effects may be via separate signal transduction pathways. Intracellular H2S/NO levels may be maintained in a state of balance to warrant normal smooth muscle motility." @default.
• W2008442981 created "2016-06-24" @default.
• W2008442981 creator A5015991076 @default.
• W2008442981 creator A5023436282 @default.
• W2008442981 creator A5024986105 @default.
• W2008442981 creator A5032872423 @default.
• W2008442981 creator A5034313532 @default.
• W2008442981 creator A5037661030 @default.
• W2008442981 creator A5052411651 @default.
• W2008442981 creator A5063467902 @default.
• W2008442981 creator A5082708183 @default.
• W2008442981 date "2013-11-01" @default.
• W2008442981 modified "2023-09-27" @default.
• W2008442981 title "Different regulatory effects of hydrogen sulfide and nitric oxide on gastric motility in mice" @default.
• W2008442981 cites W1511717229 @default.
• W2008442981 cites W1564473000 @default.
• W2008442981 cites W1973592190 @default.
• W2008442981 cites W1975072795 @default.
• W2008442981 cites W1980742612 @default.
• W2008442981 cites W1982507137 @default.
• W2008442981 cites W1983029157 @default.
• W2008442981 cites W1987639801 @default.
• W2008442981 cites W1989827285 @default.
• W2008442981 cites W1994413665 @default.
• W2008442981 cites W1996675559 @default.
• W2008442981 cites W1996709911 @default.
• W2008442981 cites W1997220104 @default.
• W2008442981 cites W2005980540 @default.
• W2008442981 cites W2015407072 @default.
• W2008442981 cites W2025905719 @default.
• W2008442981 cites W2028516053 @default.
• W2008442981 cites W2030238021 @default.
• W2008442981 cites W2043239658 @default.
• W2008442981 cites W2045395767 @default.
• W2008442981 cites W2046485211 @default.
• W2008442981 cites W2047888981 @default.
• W2008442981 cites W2069161855 @default.
• W2008442981 cites W2070132733 @default.
• W2008442981 cites W2081447694 @default.
• W2008442981 cites W2087330866 @default.
• W2008442981 cites W2087485118 @default.
• W2008442981 cites W2125421690 @default.
• W2008442981 cites W2134382614 @default.
• W2008442981 cites W2139556561 @default.
• W2008442981 cites W2141610173 @default.
• W2008442981 cites W2147883129 @default.
• W2008442981 cites W2157257377 @default.
• W2008442981 cites W2159558963 @default.
• W2008442981 cites W2183660367 @default.
• W2008442981 cites W2218322108 @default.
• W2008442981 cites W2234541988 @default.
• W2008442981 doi "https://doi.org/10.1016/j.ejphar.2013.10.017" @default.
• W2008442981 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24157974" @default.
• W2008442981 hasPublicationYear "2013" @default.
• W2008442981 type Work @default.
• W2008442981 sameAs 2008442981 @default.
• W2008442981 citedByCount "16" @default.
• W2008442981 countsByYear W20084429812014 @default.
• W2008442981 countsByYear W20084429812015 @default.
• W2008442981 countsByYear W20084429812016 @default.
• W2008442981 countsByYear W20084429812017 @default.
• W2008442981 countsByYear W20084429812018 @default.
• W2008442981 countsByYear W20084429812019 @default.
• W2008442981 countsByYear W20084429812020 @default.
• W2008442981 countsByYear W20084429812022 @default.
• W2008442981 crossrefType "journal-article" @default.
• W2008442981 hasAuthorship W2008442981A5015991076 @default.
• W2008442981 hasAuthorship W2008442981A5023436282 @default.
• W2008442981 hasAuthorship W2008442981A5024986105 @default.
• W2008442981 hasAuthorship W2008442981A5032872423 @default.
• W2008442981 hasAuthorship W2008442981A5034313532 @default.
• W2008442981 hasAuthorship W2008442981A5037661030 @default.
• W2008442981 hasAuthorship W2008442981A5052411651 @default.
• W2008442981 hasAuthorship W2008442981A5063467902 @default.
• W2008442981 hasAuthorship W2008442981A5082708183 @default.
• W2008442981 hasConcept C126322002 @default.
• W2008442981 hasConcept C134018914 @default.
• W2008442981 hasConcept C16525657 @default.
• W2008442981 hasConcept C178790620 @default.
• W2008442981 hasConcept C181199279 @default.
• W2008442981 hasConcept C185592680 @default.
• W2008442981 hasConcept C2777622882 @default.
• W2008442981 hasConcept C2779201268 @default.
• W2008442981 hasConcept C2780519940 @default.
• W2008442981 hasConcept C2780564542 @default.
• W2008442981 hasConcept C518881349 @default.
• W2008442981 hasConcept C519581460 @default.
• W2008442981 hasConcept C55493867 @default.
• W2008442981 hasConcept C58207958 @default.
• W2008442981 hasConcept C71924100 @default.
• W2008442981 hasConcept C86803240 @default.
• W2008442981 hasConcept C95444343 @default.
• W2008442981 hasConceptScore W2008442981C126322002 @default.
• W2008442981 hasConceptScore W2008442981C134018914 @default.
• W2008442981 hasConceptScore W2008442981C16525657 @default.
• W2008442981 hasConceptScore W2008442981C178790620 @default.
• W2008442981 hasConceptScore W2008442981C181199279 @default.
• W2008442981 hasConceptScore W2008442981C185592680 @default.

• next