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• W2008449904 abstract "이온이 첨가된 BCP(biphasic calcium phosphate) 분말을 제조하기 위하여 <TEX>$Ca(NO_3)_2{cdot}4H_2O$</TEX>, <TEX>$(NH_4)_2HPO_4$</TEX>를 출발 물질로 공침법(co-precipitation process)을 이용하여 합성하였다. Si-BCP 합성을 위하여 TEOS를 Mg-BCP 합성을 위해서는 <TEX>$Mg(NO_3)_2{cdot}6H_2O$</TEX>를 사용하였다. 합성된 분말의 열처리 후 결정상을 분석한 결과 HAp와 <TEX>${beta}$</TEX>-TCP가 혼재된 상을 관찰할 수 있었다. 분광학적 분석에서도 인산칼슘의 <TEX>$PO^{3-}_4$</TEX>와 <TEX>$OH^-$</TEX> 그룹에 해당하는 밴드도 관찰되었다. 이온이 첨가된 BCP 분말의 생체활성 거동을 평가하기 위하여 Hanks' Balanced Salt Solution(HBSS)에 침적시켜 시간에 따라 형상의 변화 및 결정상을 분석한 결과, 두 샘플 모두에서 빠른 표면 활성을 나타내었다. 세포 성장률 평가에서도 대조군에 비하여 세포성장률이 우수함을 관찰하였다. The co-precipitation technique has been applied to synthesize biphasic calcium phosphate (BCP). <TEX>$Ca(NO_3)_2{cdot}4H_2O$</TEX>, <TEX>$(NH_4)_2HPO_4$</TEX>, TEOS and <TEX>$Mg(NO_3)_2{cdot}6H_2O$</TEX> as the starting materials was used. After the heat treatment of powder crystalline phases HAp and <TEX>${beta}$</TEX>-TCP analysis showed a mixed phase. The overall spectra appear to have mainly two modes corresponding to characteristic <TEX>$PO^{3-}_4$</TEX> and <TEX>$OH^-$</TEX> groups. After immersion in Hanks' Balanced Salt Solution (HBSS) for 1 week a precipitation started to be formed with individual small granules on the specimen surface. An MTT assay indicated that ionic substituted BCP powders had no cytotoxic effects on MG-63 cells, and that they have good biocompatibility." @default.
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• W2008449904 date "2012-04-30" @default.
• W2008449904 modified "2023-09-28" @default.
• W2008449904 title "Bioactivity behavior of Si and Mg ion-substituted biphasic calcium phosphate powders" @default.
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• W2008449904 doi "https://doi.org/10.6111/jkcgct.2012.22.2.092" @default.
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