Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008482719> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2008482719 endingPage "518" @default.
- W2008482719 startingPage "511" @default.
- W2008482719 abstract "1. The effect of stimulation of adenylate cyclase by pancreozymin-C-octapeptide on the cyclic AMP level of rat pancreatic fragments has been investigated. 2. In normal Krebs-Ringer bicarbonate medium pancreozymin-C-octapeptide causes a slight increase in pancreatic cyclic AMP level; this increase can be considerably enhanced by incubation in a calcium-free incubation medium. 3. The dose-response curve for pancreozymin-C-octapeptide in calcium-free medium is shifted to lower peptide concentrations, compared to the curve in normal Krebs-Ringer bicarbonate medium. 4. The maximal stimulatory effect of pancreozymin-C-octapeptide is obtained at a 1-methyl-3-isobutylxanthine concentration of 10 mM. 5. It suffices to lower the Ca2+-concentration of the medium from 2.5 to 1.5 mM to get the maximal increase in cyclic AMP content under influence of pancreozymin-C-octapeptide. 6. It is concluded that extracellular calcium antagonizes the stimulation of adenylate cyclase by pancreozymin-C-octapeptide. This suggests that a low cytoplasmic Ca2+-concentration is required for the maximal response of acinar cell adenylate cyclase to pancreozymin." @default.
- W2008482719 created "2016-06-24" @default.
- W2008482719 creator A5014137007 @default.
- W2008482719 creator A5037099401 @default.
- W2008482719 creator A5039644025 @default.
- W2008482719 creator A5085595805 @default.
- W2008482719 date "1980-07-01" @default.
- W2008482719 modified "2023-10-15" @default.
- W2008482719 title "Rat pancreas adenylate cyclase VII. Effect of extracellular calcium on pancreozymin-induced cyclic AMP formation" @default.
- W2008482719 cites W1500966449 @default.
- W2008482719 cites W1516894702 @default.
- W2008482719 cites W1537198121 @default.
- W2008482719 cites W1585122688 @default.
- W2008482719 cites W1596066742 @default.
- W2008482719 cites W1622653499 @default.
- W2008482719 cites W1775749144 @default.
- W2008482719 cites W1828706661 @default.
- W2008482719 cites W1965936557 @default.
- W2008482719 cites W1975132093 @default.
- W2008482719 cites W1979868659 @default.
- W2008482719 cites W1983089351 @default.
- W2008482719 cites W1984166578 @default.
- W2008482719 cites W1990968812 @default.
- W2008482719 cites W1995152430 @default.
- W2008482719 cites W1999970975 @default.
- W2008482719 cites W2006329375 @default.
- W2008482719 cites W2028577012 @default.
- W2008482719 cites W2029729367 @default.
- W2008482719 cites W2039877978 @default.
- W2008482719 cites W2052378479 @default.
- W2008482719 cites W2064416952 @default.
- W2008482719 cites W2087010591 @default.
- W2008482719 cites W2088335303 @default.
- W2008482719 cites W2177450008 @default.
- W2008482719 cites W2178265833 @default.
- W2008482719 cites W2267011861 @default.
- W2008482719 cites W45574617 @default.
- W2008482719 doi "https://doi.org/10.1016/0304-4165(80)90005-7" @default.
- W2008482719 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6249387" @default.
- W2008482719 hasPublicationYear "1980" @default.
- W2008482719 type Work @default.
- W2008482719 sameAs 2008482719 @default.
- W2008482719 citedByCount "5" @default.
- W2008482719 countsByYear W20084827192019 @default.
- W2008482719 crossrefType "journal-article" @default.
- W2008482719 hasAuthorship W2008482719A5014137007 @default.
- W2008482719 hasAuthorship W2008482719A5037099401 @default.
- W2008482719 hasAuthorship W2008482719A5039644025 @default.
- W2008482719 hasAuthorship W2008482719A5085595805 @default.
- W2008482719 hasConcept C126322002 @default.
- W2008482719 hasConcept C134018914 @default.
- W2008482719 hasConcept C180526460 @default.
- W2008482719 hasConcept C181199279 @default.
- W2008482719 hasConcept C185592680 @default.
- W2008482719 hasConcept C24998067 @default.
- W2008482719 hasConcept C25642318 @default.
- W2008482719 hasConcept C2780069284 @default.
- W2008482719 hasConcept C2781112554 @default.
- W2008482719 hasConcept C28406088 @default.
- W2008482719 hasConcept C519063684 @default.
- W2008482719 hasConcept C55493867 @default.
- W2008482719 hasConcept C71924100 @default.
- W2008482719 hasConcept C86803240 @default.
- W2008482719 hasConceptScore W2008482719C126322002 @default.
- W2008482719 hasConceptScore W2008482719C134018914 @default.
- W2008482719 hasConceptScore W2008482719C180526460 @default.
- W2008482719 hasConceptScore W2008482719C181199279 @default.
- W2008482719 hasConceptScore W2008482719C185592680 @default.
- W2008482719 hasConceptScore W2008482719C24998067 @default.
- W2008482719 hasConceptScore W2008482719C25642318 @default.
- W2008482719 hasConceptScore W2008482719C2780069284 @default.
- W2008482719 hasConceptScore W2008482719C2781112554 @default.
- W2008482719 hasConceptScore W2008482719C28406088 @default.
- W2008482719 hasConceptScore W2008482719C519063684 @default.
- W2008482719 hasConceptScore W2008482719C55493867 @default.
- W2008482719 hasConceptScore W2008482719C71924100 @default.
- W2008482719 hasConceptScore W2008482719C86803240 @default.
- W2008482719 hasIssue "4" @default.
- W2008482719 hasLocation W20084827191 @default.
- W2008482719 hasLocation W20084827192 @default.
- W2008482719 hasOpenAccess W2008482719 @default.
- W2008482719 hasPrimaryLocation W20084827191 @default.
- W2008482719 hasRelatedWork W1578076358 @default.
- W2008482719 hasRelatedWork W180243494 @default.
- W2008482719 hasRelatedWork W1964888906 @default.
- W2008482719 hasRelatedWork W1983113419 @default.
- W2008482719 hasRelatedWork W2032355380 @default.
- W2008482719 hasRelatedWork W2053922838 @default.
- W2008482719 hasRelatedWork W2159620470 @default.
- W2008482719 hasRelatedWork W2406327875 @default.
- W2008482719 hasRelatedWork W2419940757 @default.
- W2008482719 hasRelatedWork W3103481565 @default.
- W2008482719 hasVolume "630" @default.
- W2008482719 isParatext "false" @default.
- W2008482719 isRetracted "false" @default.
- W2008482719 magId "2008482719" @default.
- W2008482719 workType "article" @default.