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• W2008485259 abstract "We report experiments that test the model that in Xenopus laevis, RNA polymerase I is handed over in a conservative fashion from the T3 terminator to the adjacent gene promoter. We have introduced transcription-terminating lesions into the ribosomal DNA repeat by irradiating cultured cells with ultraviolet light. We used isolated nuclei to measure the effect of such lesions on transcription. UV damage sufficient to prevent all elongating RNA polymerase from reaching T3 from upstream had no adverse effect on the density of RNA polymerase at the very 5' end of the gene. We conclude that high rates of transcription initiation at the gene promoter do not depend upon polymerase passing from one repeat to the next or on polymerase initiating at the spacer promoters." @default.
• W2008485259 created "2016-06-24" @default.
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• W2008485259 date "1989-05-01" @default.
• W2008485259 modified "2023-10-16" @default.
• W2008485259 title "High initiation rates at the ribosomal gene promoter do not depend upon spacer transcription." @default.
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• W2008485259 doi "https://doi.org/10.1073/pnas.86.9.3155" @default.
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