Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008541844> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2008541844 endingPage "451" @default.
- W2008541844 startingPage "448" @default.
- W2008541844 abstract "The fourth component of complement (C4) is encoded by two separate but linked loci (C4A and C4B), each of which produces functionally active C4. Although C4A and C4B share certain antigenic and functional characteristics that identify them as C4, they differ with respect to other structural and functional properties. For example, C4B possesses four times the functional hemolytic activity of C4A. This suggests that homozygous deficiency of C4B might be associated with an increased susceptibility to infection. Forty-six children with bacterial meningitis were examined. Of these, 5 (10.9%) were homozygous deficient for C4B versus 7 (3.1%) of 223 controls (P = 0.038). There was no relation between the prevalence of heterozygous C4B deficiency and meningitis or between the prevalence of either homozygous or heterozygous C4A deficiency and meningitis. These results suggest that homozygous C4B deficiency is a relatively common immunodeficiency disorder that is clinically significant and predisposes children to bacterial meningitis." @default.
- W2008541844 created "2016-06-24" @default.
- W2008541844 creator A5018476333 @default.
- W2008541844 creator A5045041188 @default.
- W2008541844 creator A5059746563 @default.
- W2008541844 creator A5065852957 @default.
- W2008541844 creator A5077495093 @default.
- W2008541844 date "1989-09-01" @default.
- W2008541844 modified "2023-09-26" @default.
- W2008541844 title "Association of Homozygous C4B Deficiency with Bacterial Meningitis" @default.
- W2008541844 cites W1486381049 @default.
- W2008541844 cites W1537706933 @default.
- W2008541844 cites W1600693909 @default.
- W2008541844 cites W1977909365 @default.
- W2008541844 cites W1985401925 @default.
- W2008541844 cites W2006207130 @default.
- W2008541844 cites W2025386975 @default.
- W2008541844 cites W2039912342 @default.
- W2008541844 cites W2053638794 @default.
- W2008541844 cites W2064536780 @default.
- W2008541844 cites W2068701764 @default.
- W2008541844 cites W2076418180 @default.
- W2008541844 cites W2083192361 @default.
- W2008541844 cites W2088883442 @default.
- W2008541844 cites W2130970849 @default.
- W2008541844 cites W2149550178 @default.
- W2008541844 cites W2151260681 @default.
- W2008541844 cites W2166708018 @default.
- W2008541844 cites W2174235784 @default.
- W2008541844 cites W2321919937 @default.
- W2008541844 cites W2414230018 @default.
- W2008541844 cites W2520171423 @default.
- W2008541844 cites W2399657022 @default.
- W2008541844 doi "https://doi.org/10.1093/infdis/160.3.448" @default.
- W2008541844 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2788199" @default.
- W2008541844 hasPublicationYear "1989" @default.
- W2008541844 type Work @default.
- W2008541844 sameAs 2008541844 @default.
- W2008541844 citedByCount "65" @default.
- W2008541844 countsByYear W20085418442014 @default.
- W2008541844 countsByYear W20085418442016 @default.
- W2008541844 countsByYear W20085418442019 @default.
- W2008541844 countsByYear W20085418442020 @default.
- W2008541844 countsByYear W20085418442021 @default.
- W2008541844 crossrefType "journal-article" @default.
- W2008541844 hasAuthorship W2008541844A5018476333 @default.
- W2008541844 hasAuthorship W2008541844A5045041188 @default.
- W2008541844 hasAuthorship W2008541844A5059746563 @default.
- W2008541844 hasAuthorship W2008541844A5065852957 @default.
- W2008541844 hasAuthorship W2008541844A5077495093 @default.
- W2008541844 hasConcept C104317684 @default.
- W2008541844 hasConcept C111684460 @default.
- W2008541844 hasConcept C187212893 @default.
- W2008541844 hasConcept C203014093 @default.
- W2008541844 hasConcept C2777327493 @default.
- W2008541844 hasConcept C2781026528 @default.
- W2008541844 hasConcept C3018430615 @default.
- W2008541844 hasConcept C54355233 @default.
- W2008541844 hasConcept C71924100 @default.
- W2008541844 hasConcept C86803240 @default.
- W2008541844 hasConcept C8891405 @default.
- W2008541844 hasConcept C90630246 @default.
- W2008541844 hasConceptScore W2008541844C104317684 @default.
- W2008541844 hasConceptScore W2008541844C111684460 @default.
- W2008541844 hasConceptScore W2008541844C187212893 @default.
- W2008541844 hasConceptScore W2008541844C203014093 @default.
- W2008541844 hasConceptScore W2008541844C2777327493 @default.
- W2008541844 hasConceptScore W2008541844C2781026528 @default.
- W2008541844 hasConceptScore W2008541844C3018430615 @default.
- W2008541844 hasConceptScore W2008541844C54355233 @default.
- W2008541844 hasConceptScore W2008541844C71924100 @default.
- W2008541844 hasConceptScore W2008541844C86803240 @default.
- W2008541844 hasConceptScore W2008541844C8891405 @default.
- W2008541844 hasConceptScore W2008541844C90630246 @default.
- W2008541844 hasIssue "3" @default.
- W2008541844 hasLocation W20085418441 @default.
- W2008541844 hasLocation W20085418442 @default.
- W2008541844 hasOpenAccess W2008541844 @default.
- W2008541844 hasPrimaryLocation W20085418441 @default.
- W2008541844 hasRelatedWork W1566700659 @default.
- W2008541844 hasRelatedWork W2008541844 @default.
- W2008541844 hasRelatedWork W2013551692 @default.
- W2008541844 hasRelatedWork W2036126415 @default.
- W2008541844 hasRelatedWork W2059562987 @default.
- W2008541844 hasRelatedWork W2080255759 @default.
- W2008541844 hasRelatedWork W2151160219 @default.
- W2008541844 hasRelatedWork W2416775513 @default.
- W2008541844 hasRelatedWork W2952520167 @default.
- W2008541844 hasRelatedWork W29888215 @default.
- W2008541844 hasVolume "160" @default.
- W2008541844 isParatext "false" @default.
- W2008541844 isRetracted "false" @default.
- W2008541844 magId "2008541844" @default.
- W2008541844 workType "article" @default.