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• W2008542909 abstract "Objective: To evaluate the association between exposure to chlorinated solvents and cancer. Methods: We conducted a case–control study of occupational exposures and cancer in Montreal, Quebec, Canada, including 3730 cancer cases and 533 population controls. Occupational exposures were derived using a combination of subject-reported job history and expert assessment. We examined the associations between two chemical families and six chlorinated solvents with 11 sites of cancer. Results: The majority of the associations examined were null, although many were based on small numbers. We found two significantly elevated odds ratios (ORs), one between perchloroethylene and prostate cancer (OR = 4.3; 95% CI: 1.4 to 13) and another between trichloroethylene and melanoma (OR = 3.2; 95% CI: 1.0 to 9.9). Conclusions: There was little evidence of associations between chlorinated solvents and cancer. Limited power precludes strong inferences about absence of risk. We raise hypotheses about two possible associations: perchloroethylene with prostate cancer and trichloroethylene with melanoma." @default.
• W2008542909 created "2016-06-24" @default.
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• W2008542909 date "2013-02-01" @default.
• W2008542909 modified "2023-10-03" @default.
• W2008542909 title "Risk of Selected Cancers due to Occupational Exposure to Chlorinated Solvents in a Case–Control Study in Montreal" @default.
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• W2008542909 doi "https://doi.org/10.1097/jom.0b013e3182728eab" @default.
• W2008542909 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23147555" @default.
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