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• W2008551019 abstract "A general preparation of functionalized primary chiral amines and amides from propargylamines has been developed. The chirality is established by an enantioselective three-component reaction of an aldehyde, a terminal alkyne and a secondary amine in the presence of copper(I) bromide/Quinap as the catalytic system leading to chiral propargylamines in high yields and enantioselectivities. Functionalization and reduction leads to various primary amines and amides." @default.
• W2008551019 created "2016-06-24" @default.
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• W2008551019 date "2005-11-01" @default.
• W2008551019 modified "2023-10-14" @default.
• W2008551019 title "Preparation of functionalized primary chiral amines and amides via an enantioselective three-component synthesis of propargylamines" @default.
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• W2008551019 doi "https://doi.org/10.1016/j.tet.2005.08.064" @default.
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