FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008575691> ?p ?o ?g. }

• W2008575691 endingPage "237" @default.
• W2008575691 startingPage "229" @default.
• W2008575691 abstract "The rat forced-swimming test (FST) is widely used for screening substances with a potential antidepressant effect. The rat immobility shown in the FST has been interpreted as “behavioral despair” and has been suggested as an animal model of human depression. In the following series of experiments it is shown that measuring rat mobility by an automatic recording device is more accurate than measuring immobility time by direct observation (Experiment 1 and 5). The automatic recording procedure was tested with imipramine and mianserin showing similar results to those reported in the literature using a direct observation procedure by the researcher (Experiment 2). In Experiment 3 it was demonstrated that: (a) rat mobility decreased with experience, (b) switching water depth on Day 2 of the test increased mobility and (c) anisomycin acts as a false positive. In Experiment 4 the possible state dependent effect of imipramine in the FST was studied. The effect of imipramine on rat behavior in the FST is not state dependent. The imipramine-saline group shows greater mobility than the saline-saline group and does not differentiate from the imipramine-imipramine group. Thus, it was suggested that imipramine could interfere with the acquisition and/or consolidation processes. In Experiment 5, it is shown that a single dose of 25 mg/kg of imipramine, administered before or immediately after training on Day 1, increases rat's mobility on Day 2, thus suggesting that imipramine alters the consolidation process. From these results it is suggested that the behavioral process involved in the FST is “learning to be immobile” instead of “behavioral despair” as previously suggested in the literature." @default.
• W2008575691 created "2016-06-24" @default.
• W2008575691 creator A5013261333 @default.
• W2008575691 creator A5050407361 @default.
• W2008575691 creator A5075905467 @default.
• W2008575691 creator A5083992742 @default.
• W2008575691 date "1989-08-01" @default.
• W2008575691 modified "2023-10-11" @default.
• W2008575691 title "Learned immobility explains the behavior of rats in the forced swimming test" @default.
• W2008575691 cites W1968235275 @default.
• W2008575691 cites W1969714501 @default.
• W2008575691 cites W1973386992 @default.
• W2008575691 cites W1975633226 @default.
• W2008575691 cites W1978345334 @default.
• W2008575691 cites W1978503969 @default.
• W2008575691 cites W1979581229 @default.
• W2008575691 cites W1980849606 @default.
• W2008575691 cites W1984542848 @default.
• W2008575691 cites W1984561249 @default.
• W2008575691 cites W1986568950 @default.
• W2008575691 cites W1988223009 @default.
• W2008575691 cites W1988927861 @default.
• W2008575691 cites W1993288247 @default.
• W2008575691 cites W1996031147 @default.
• W2008575691 cites W1998687342 @default.
• W2008575691 cites W2000025073 @default.
• W2008575691 cites W2000689387 @default.
• W2008575691 cites W2009039788 @default.
• W2008575691 cites W2010626267 @default.
• W2008575691 cites W2013478073 @default.
• W2008575691 cites W2013732364 @default.
• W2008575691 cites W2014964322 @default.
• W2008575691 cites W2018712437 @default.
• W2008575691 cites W2026564161 @default.
• W2008575691 cites W2029291309 @default.
• W2008575691 cites W2029553172 @default.
• W2008575691 cites W2036450821 @default.
• W2008575691 cites W2045908170 @default.
• W2008575691 cites W2047079927 @default.
• W2008575691 cites W2047191222 @default.
• W2008575691 cites W2048602266 @default.
• W2008575691 cites W2052376597 @default.
• W2008575691 cites W2053141683 @default.
• W2008575691 cites W2054631886 @default.
• W2008575691 cites W2057125358 @default.
• W2008575691 cites W2068405118 @default.
• W2008575691 cites W2070703400 @default.
• W2008575691 cites W2076048389 @default.
• W2008575691 cites W2077997956 @default.
• W2008575691 cites W2078069646 @default.
• W2008575691 cites W2083752312 @default.
• W2008575691 cites W208800884 @default.
• W2008575691 cites W2089299823 @default.
• W2008575691 cites W2090475734 @default.
• W2008575691 cites W2091845852 @default.
• W2008575691 cites W2093334851 @default.
• W2008575691 cites W2113962949 @default.
• W2008575691 cites W2117879877 @default.
• W2008575691 cites W2133114116 @default.
• W2008575691 cites W2137493359 @default.
• W2008575691 cites W2140270335 @default.
• W2008575691 cites W2168870306 @default.
• W2008575691 cites W2435906727 @default.
• W2008575691 doi "https://doi.org/10.1016/0031-9384(89)90261-8" @default.
• W2008575691 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2602464" @default.
• W2008575691 hasPublicationYear "1989" @default.
• W2008575691 type Work @default.
• W2008575691 sameAs 2008575691 @default.
• W2008575691 citedByCount "154" @default.
• W2008575691 countsByYear W20085756912012 @default.
• W2008575691 countsByYear W20085756912013 @default.
• W2008575691 countsByYear W20085756912014 @default.
• W2008575691 countsByYear W20085756912015 @default.
• W2008575691 countsByYear W20085756912016 @default.
• W2008575691 countsByYear W20085756912017 @default.
• W2008575691 countsByYear W20085756912018 @default.
• W2008575691 countsByYear W20085756912019 @default.
• W2008575691 countsByYear W20085756912020 @default.
• W2008575691 countsByYear W20085756912021 @default.
• W2008575691 countsByYear W20085756912022 @default.
• W2008575691 countsByYear W20085756912023 @default.
• W2008575691 crossrefType "journal-article" @default.
• W2008575691 hasAuthorship W2008575691A5013261333 @default.
• W2008575691 hasAuthorship W2008575691A5050407361 @default.
• W2008575691 hasAuthorship W2008575691A5075905467 @default.
• W2008575691 hasAuthorship W2008575691A5083992742 @default.
• W2008575691 hasConcept C126322002 @default.
• W2008575691 hasConcept C134018914 @default.
• W2008575691 hasConcept C136569192 @default.
• W2008575691 hasConcept C142724271 @default.
• W2008575691 hasConcept C15744967 @default.
• W2008575691 hasConcept C169760540 @default.
• W2008575691 hasConcept C184235292 @default.
• W2008575691 hasConcept C185592680 @default.
• W2008575691 hasConcept C204787440 @default.
• W2008575691 hasConcept C2777397205 @default.
• W2008575691 hasConcept C2778073123 @default.
• W2008575691 hasConcept C2779145073 @default.

• next