FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008587413> ?p ?o ?g. }

• W2008587413 endingPage "174" @default.
• W2008587413 startingPage "165" @default.
• W2008587413 abstract "Cerretelli, Paolo, Mauro Marzorati, and Claudio Marconi. Muscle bioenergetics and metabolic control at altitude. High Alt. Med. Biol. 10: 165–174, 2009.—High altitude functional data, particularly those obtained on humans in the field by conventional techniques, appear to be often affected by a large variability that does not seem to be justified by the characteristics of the research protocols and by the adopted experimental procedures which, in most cases, are “state of the art”. This is also evident by the frequent occurrence of debates (e.g. “point – counterpoint” contributions by specialists in the Journal of Applied Physiology) on issues whose interpretation was taken for granted. The appearance of an exclusive new player, the multi-gene transcription protein Hypoxia Inducible Factor (HIF-1) recognized as the master regulator of cell hypoxic signaling, opens a new scenario. Indeed, among the genes regulated by HIF-1, besides those expressing EPO and VEGF controlling erythropoiesis and angiogenesis, respectively, there are hundreds of other genes whose products play a large number of metabolic and transport functions. The aim of the present work is to revisit some earlier results that have been generally overlooked, in order to provide them with a more comprehensive interpretation. This has been done on the basis of work on cell hypoxic signaling including some metabolic players recently identified by muscle proteome analysis. Particular emphasis has been laid on the molecular interpretation of findings such as improved metabolic efficiency of locomotion in chronic hypoxia, origin and significance of an apparent misnomer such as the so-called “lactate paradox”, and the physiological meaning of the muscle mitochondrial mass reduction in both altitude natives and acclimatized lowlanders." @default.
• W2008587413 created "2016-06-24" @default.
• W2008587413 creator A5003130008 @default.
• W2008587413 creator A5053810598 @default.
• W2008587413 creator A5069472150 @default.
• W2008587413 date "2009-06-01" @default.
• W2008587413 modified "2023-09-25" @default.
• W2008587413 title "Muscle Bioenergetics and Metabolic Control at Altitude" @default.
• W2008587413 cites W128494275 @default.
• W2008587413 cites W1580746914 @default.
• W2008587413 cites W1765130822 @default.
• W2008587413 cites W1799768544 @default.
• W2008587413 cites W1869935384 @default.
• W2008587413 cites W1895314414 @default.
• W2008587413 cites W1906995499 @default.
• W2008587413 cites W1919144364 @default.
• W2008587413 cites W1939003743 @default.
• W2008587413 cites W1952978044 @default.
• W2008587413 cites W1965827991 @default.
• W2008587413 cites W1973695541 @default.
• W2008587413 cites W1974513697 @default.
• W2008587413 cites W1977375398 @default.
• W2008587413 cites W1980344459 @default.
• W2008587413 cites W1987813431 @default.
• W2008587413 cites W1991684938 @default.
• W2008587413 cites W1994458323 @default.
• W2008587413 cites W1995061952 @default.
• W2008587413 cites W2003296283 @default.
• W2008587413 cites W2006039905 @default.
• W2008587413 cites W2017910536 @default.
• W2008587413 cites W2019011438 @default.
• W2008587413 cites W2024277225 @default.
• W2008587413 cites W2027705428 @default.
• W2008587413 cites W2033958147 @default.
• W2008587413 cites W2040603216 @default.
• W2008587413 cites W2043558141 @default.
• W2008587413 cites W2046694213 @default.
• W2008587413 cites W2047545717 @default.
• W2008587413 cites W2049728832 @default.
• W2008587413 cites W2054987125 @default.
• W2008587413 cites W2060669952 @default.
• W2008587413 cites W2071427069 @default.
• W2008587413 cites W2072410196 @default.
• W2008587413 cites W2073269398 @default.
• W2008587413 cites W2076553390 @default.
• W2008587413 cites W2098902167 @default.
• W2008587413 cites W2098933494 @default.
• W2008587413 cites W2103907815 @default.
• W2008587413 cites W2112818694 @default.
• W2008587413 cites W2129665028 @default.
• W2008587413 cites W2132861747 @default.
• W2008587413 cites W2149635046 @default.
• W2008587413 cites W2165235603 @default.
• W2008587413 cites W2173023588 @default.
• W2008587413 cites W2173429356 @default.
• W2008587413 cites W2204786782 @default.
• W2008587413 cites W2220003451 @default.
• W2008587413 cites W2238719175 @default.
• W2008587413 cites W2272788938 @default.
• W2008587413 cites W2343361883 @default.
• W2008587413 cites W2411571381 @default.
• W2008587413 cites W2415577897 @default.
• W2008587413 cites W4249079579 @default.
• W2008587413 doi "https://doi.org/10.1089/ham.2008.1096" @default.
• W2008587413 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19480606" @default.
• W2008587413 hasPublicationYear "2009" @default.
• W2008587413 type Work @default.
• W2008587413 sameAs 2008587413 @default.
• W2008587413 citedByCount "28" @default.
• W2008587413 countsByYear W20085874132012 @default.
• W2008587413 countsByYear W20085874132013 @default.
• W2008587413 countsByYear W20085874132014 @default.
• W2008587413 countsByYear W20085874132015 @default.
• W2008587413 countsByYear W20085874132016 @default.
• W2008587413 countsByYear W20085874132018 @default.
• W2008587413 countsByYear W20085874132019 @default.
• W2008587413 countsByYear W20085874132020 @default.
• W2008587413 countsByYear W20085874132021 @default.
• W2008587413 countsByYear W20085874132023 @default.
• W2008587413 crossrefType "journal-article" @default.
• W2008587413 hasAuthorship W2008587413A5003130008 @default.
• W2008587413 hasAuthorship W2008587413A5053810598 @default.
• W2008587413 hasAuthorship W2008587413A5069472150 @default.
• W2008587413 hasConcept C100206155 @default.
• W2008587413 hasConcept C104317684 @default.
• W2008587413 hasConcept C126322002 @default.
• W2008587413 hasConcept C160450060 @default.
• W2008587413 hasConcept C178790620 @default.
• W2008587413 hasConcept C185592680 @default.
• W2008587413 hasConcept C2778248108 @default.
• W2008587413 hasConcept C2779703530 @default.
• W2008587413 hasConcept C28859421 @default.
• W2008587413 hasConcept C42407357 @default.
• W2008587413 hasConcept C540031477 @default.
• W2008587413 hasConcept C54355233 @default.
• W2008587413 hasConcept C60644358 @default.
• W2008587413 hasConcept C6929976 @default.
• W2008587413 hasConcept C71924100 @default.

• next