Matches in SemOpenAlex for { <https://semopenalex.org/work/W2008598112> ?p ?o ?g. }
- W2008598112 endingPage "347" @default.
- W2008598112 startingPage "341" @default.
- W2008598112 abstract "Hyperstructures or modules have been proposed to constitute a level of organisation intermediate between macromolecules and whole cells. In this model of intracellular organisation, hyperstructures compete and collaborate for existence within the membrane and cytoplasm. Those directly involved in the cell cycle include initiation, replication and division hyperstructures based on DnaA, SeqA and the 2-minute cluster, respectively. During the run-up to initiation, the mass to DNA ratio increases and, we contend, differential gene expression leads to some hyperstructures becoming more active and stable than others. This results in a drop in the diversity of hyperstructures, some of which release DnaA as they dissociate, and a DnaA-initiation hyperstructure forms. Subsequent DNA replication and cell division generate different daughter cells containing different hyperstructures. This has the advantage of increasing the phenotypic diversity of the population. In developing this model, we also invoke hyperstructures in the partitioning of origins of replication." @default.
- W2008598112 created "2016-06-24" @default.
- W2008598112 creator A5012948668 @default.
- W2008598112 creator A5022074580 @default.
- W2008598112 creator A5040793464 @default.
- W2008598112 creator A5048194533 @default.
- W2008598112 creator A5077550115 @default.
- W2008598112 date "2002-04-01" @default.
- W2008598112 modified "2023-09-27" @default.
- W2008598112 title "Hypothesis: hyperstructures regulate initiation in Escherichia coli and other bacteria" @default.
- W2008598112 cites W1502935855 @default.
- W2008598112 cites W1557642928 @default.
- W2008598112 cites W1557646389 @default.
- W2008598112 cites W1644749979 @default.
- W2008598112 cites W1965778416 @default.
- W2008598112 cites W1976110793 @default.
- W2008598112 cites W1984435743 @default.
- W2008598112 cites W1985926809 @default.
- W2008598112 cites W1990866893 @default.
- W2008598112 cites W1992419142 @default.
- W2008598112 cites W1996336244 @default.
- W2008598112 cites W2005102943 @default.
- W2008598112 cites W2005160671 @default.
- W2008598112 cites W2011494695 @default.
- W2008598112 cites W2012146831 @default.
- W2008598112 cites W2020282040 @default.
- W2008598112 cites W2020592675 @default.
- W2008598112 cites W2025579355 @default.
- W2008598112 cites W2033766178 @default.
- W2008598112 cites W2033867172 @default.
- W2008598112 cites W2038478484 @default.
- W2008598112 cites W2049076326 @default.
- W2008598112 cites W2054118983 @default.
- W2008598112 cites W2068155530 @default.
- W2008598112 cites W2068883756 @default.
- W2008598112 cites W2069982266 @default.
- W2008598112 cites W2073948494 @default.
- W2008598112 cites W2076710572 @default.
- W2008598112 cites W2101040320 @default.
- W2008598112 cites W2110932195 @default.
- W2008598112 cites W2113725378 @default.
- W2008598112 cites W2124072330 @default.
- W2008598112 cites W2128446385 @default.
- W2008598112 cites W2132690489 @default.
- W2008598112 cites W2136679235 @default.
- W2008598112 cites W2138278869 @default.
- W2008598112 cites W2138728546 @default.
- W2008598112 cites W2144743236 @default.
- W2008598112 cites W2168002962 @default.
- W2008598112 cites W939617381 @default.
- W2008598112 doi "https://doi.org/10.1016/s0300-9084(02)01387-1" @default.
- W2008598112 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12106913" @default.
- W2008598112 hasPublicationYear "2002" @default.
- W2008598112 type Work @default.
- W2008598112 sameAs 2008598112 @default.
- W2008598112 citedByCount "22" @default.
- W2008598112 countsByYear W20085981122012 @default.
- W2008598112 crossrefType "journal-article" @default.
- W2008598112 hasAuthorship W2008598112A5012948668 @default.
- W2008598112 hasAuthorship W2008598112A5022074580 @default.
- W2008598112 hasAuthorship W2008598112A5040793464 @default.
- W2008598112 hasAuthorship W2008598112A5048194533 @default.
- W2008598112 hasAuthorship W2008598112A5077550115 @default.
- W2008598112 hasConcept C104317684 @default.
- W2008598112 hasConcept C107827726 @default.
- W2008598112 hasConcept C1491633281 @default.
- W2008598112 hasConcept C190062978 @default.
- W2008598112 hasConcept C29537977 @default.
- W2008598112 hasConcept C54355233 @default.
- W2008598112 hasConcept C58337764 @default.
- W2008598112 hasConcept C73573662 @default.
- W2008598112 hasConcept C85813293 @default.
- W2008598112 hasConcept C86803240 @default.
- W2008598112 hasConcept C95444343 @default.
- W2008598112 hasConceptScore W2008598112C104317684 @default.
- W2008598112 hasConceptScore W2008598112C107827726 @default.
- W2008598112 hasConceptScore W2008598112C1491633281 @default.
- W2008598112 hasConceptScore W2008598112C190062978 @default.
- W2008598112 hasConceptScore W2008598112C29537977 @default.
- W2008598112 hasConceptScore W2008598112C54355233 @default.
- W2008598112 hasConceptScore W2008598112C58337764 @default.
- W2008598112 hasConceptScore W2008598112C73573662 @default.
- W2008598112 hasConceptScore W2008598112C85813293 @default.
- W2008598112 hasConceptScore W2008598112C86803240 @default.
- W2008598112 hasConceptScore W2008598112C95444343 @default.
- W2008598112 hasIssue "4" @default.
- W2008598112 hasLocation W20085981121 @default.
- W2008598112 hasLocation W20085981122 @default.
- W2008598112 hasLocation W20085981123 @default.
- W2008598112 hasOpenAccess W2008598112 @default.
- W2008598112 hasPrimaryLocation W20085981121 @default.
- W2008598112 hasRelatedWork W1734048701 @default.
- W2008598112 hasRelatedWork W1880833745 @default.
- W2008598112 hasRelatedWork W1917101767 @default.
- W2008598112 hasRelatedWork W2026535633 @default.
- W2008598112 hasRelatedWork W2039791035 @default.
- W2008598112 hasRelatedWork W2047658415 @default.
- W2008598112 hasRelatedWork W2067090293 @default.