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- W2008636706 abstract "In Brief Purpose: To determine whether there is a difference in anesthetic effect between topical proparacaine drops, 4% lidocaine solution, or 3.5% lidocaine gel, and whether this has an impact on the overall injection experience. Methods: One hundred and twenty sequential patients undergoing intravitreal injections were randomized to 1 of 3 groups: proparacaine 0.5% drops (Group 1), proparacaine + 4% lidocaine-soaked cotton tipped swabs (Group 2), or 3.5% lidocaine gel (Group 3). Discomfort associated with the lid speculum, with the needle, and with burning sensation was graded on a scale of 0 to 10 (0 = no pain, 10 = worst pain ever). The overall injection experience was graded as Excellent, Very Good, Fair, Poor, or Awful. Results: The average lid speculum pain score for Group 1 was 0.85, Group 2 was 0.50, and Group 3 was 0.65 (P = 0.32). The average needle pain score for Group 1 was 1.78, Group 2 was 1.75, and Group 3 was 1.48 (P = 0.38). The average burning pain score for Group 1 was 1.45, Group 2 was 1.58, and Group 3 was 1.13 (P = 0.23). Overall satisfaction was rated as Excellent or Very Good in 95%, 97.5%, and 92.5% of Group 1, 2, and 3 patients, respectively (P = 0.64). Conclusion: The use of topical proparacaine drops provides very effective and cost-effective anesthesia during office-based intravitreal injections. This study evaluates the effectiveness of three different topical methods of anesthesia for intravitreal injection. There was no significant difference between the three groups. Topical proparacaine drops alone provide effective anesthesia for intravitreal injection." @default.
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- W2008636706 date "2012-04-01" @default.
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- W2008636706 title "COMPARISON OF TOPICAL ANESTHETICS FOR INTRAVITREAL INJECTIONS" @default.
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- W2008636706 doi "https://doi.org/10.1097/iae.0b013e31822f27ca" @default.
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